Central diabetes insipidus secondary to COVID-19 infection: a case report
Abstract Background Novel coronavirus disease 2019 (COVID-19) mainly affects the lungs, but can involve several other organs. The diagnosis of acute and chronic sequelae is one of the challenges of COVID-19. The current literature proposes that severe acute respiratory syndrome coronavirus 2 (SARS-C...
| मुख्य लेखकों: | , , , |
|---|---|
| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
BMC
2022-05-01
|
| श्रृंखला: | BMC Endocrine Disorders |
| विषय: | |
| ऑनलाइन पहुंच: | https://doi.org/10.1186/s12902-022-01048-w |
| _version_ | 1828821754309509120 |
|---|---|
| author | Ali Yavari Zahra Sharifan Bagher Larijani Ali Mosadegh Khah |
| author_facet | Ali Yavari Zahra Sharifan Bagher Larijani Ali Mosadegh Khah |
| author_sort | Ali Yavari |
| collection | DOAJ |
| description | Abstract Background Novel coronavirus disease 2019 (COVID-19) mainly affects the lungs, but can involve several other organs. The diagnosis of acute and chronic sequelae is one of the challenges of COVID-19. The current literature proposes that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may involve the hypothalamic-pituitary axis. In this case report, we present a unique case of new-onset central diabetes insipidus secondary to the COVID-19 disease in a 54-year-old woman. Case presentation A 54-year-old woman presented with the history of excessive thirst, polyuria, and polydipsia, six weeks after being infected by COVID-19. Laboratory tests revealed low urine osmolarity and increased serum osmolarity, and the patient was diagnosed with central diabetes insipidus. After administration of nasal desmopressin, urinary osmolarity increased, and the patient's symptoms improved. However, to stabilize her condition, desmopressin treatment was required. Conclusions We reported a unique case of diabetes insipidus in a COVID-19 patient. Central diabetes insipidus may be included in clinical manifestations of the COVID-19, in case of new-onset polyuria and polydipsia following COVID-19 disease. Nevertheless, a causal relationship has not been established between the symptoms of the patient and the SARS-CoV-2 infection. |
| first_indexed | 2024-12-12T13:00:36Z |
| format | Article |
| id | doaj.art-62298b45943e4d91ae01a82d7b53b51f |
| institution | Directory Open Access Journal |
| issn | 1472-6823 |
| language | English |
| last_indexed | 2024-12-12T13:00:36Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Endocrine Disorders |
| spelling | doaj.art-62298b45943e4d91ae01a82d7b53b51f2022-12-22T00:23:48ZengBMCBMC Endocrine Disorders1472-68232022-05-012211310.1186/s12902-022-01048-wCentral diabetes insipidus secondary to COVID-19 infection: a case reportAli Yavari0Zahra Sharifan1Bagher Larijani2Ali Mosadegh Khah3Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical SciencesVirtual School of Medical Education and Management, Shahid Beheshti University of Medical SciencesEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical SciencesEndocrinology Department, AJA University of Medical ScienceAbstract Background Novel coronavirus disease 2019 (COVID-19) mainly affects the lungs, but can involve several other organs. The diagnosis of acute and chronic sequelae is one of the challenges of COVID-19. The current literature proposes that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may involve the hypothalamic-pituitary axis. In this case report, we present a unique case of new-onset central diabetes insipidus secondary to the COVID-19 disease in a 54-year-old woman. Case presentation A 54-year-old woman presented with the history of excessive thirst, polyuria, and polydipsia, six weeks after being infected by COVID-19. Laboratory tests revealed low urine osmolarity and increased serum osmolarity, and the patient was diagnosed with central diabetes insipidus. After administration of nasal desmopressin, urinary osmolarity increased, and the patient's symptoms improved. However, to stabilize her condition, desmopressin treatment was required. Conclusions We reported a unique case of diabetes insipidus in a COVID-19 patient. Central diabetes insipidus may be included in clinical manifestations of the COVID-19, in case of new-onset polyuria and polydipsia following COVID-19 disease. Nevertheless, a causal relationship has not been established between the symptoms of the patient and the SARS-CoV-2 infection.https://doi.org/10.1186/s12902-022-01048-wSARS-CoV-21Central diabetes insipidus2Complication3Desmopressin4Case report5 |
| spellingShingle | Ali Yavari Zahra Sharifan Bagher Larijani Ali Mosadegh Khah Central diabetes insipidus secondary to COVID-19 infection: a case report BMC Endocrine Disorders SARS-CoV-21 Central diabetes insipidus2 Complication3 Desmopressin4 Case report5 |
| title | Central diabetes insipidus secondary to COVID-19 infection: a case report |
| title_full | Central diabetes insipidus secondary to COVID-19 infection: a case report |
| title_fullStr | Central diabetes insipidus secondary to COVID-19 infection: a case report |
| title_full_unstemmed | Central diabetes insipidus secondary to COVID-19 infection: a case report |
| title_short | Central diabetes insipidus secondary to COVID-19 infection: a case report |
| title_sort | central diabetes insipidus secondary to covid 19 infection a case report |
| topic | SARS-CoV-21 Central diabetes insipidus2 Complication3 Desmopressin4 Case report5 |
| url | https://doi.org/10.1186/s12902-022-01048-w |
| work_keys_str_mv | AT aliyavari centraldiabetesinsipidussecondarytocovid19infectionacasereport AT zahrasharifan centraldiabetesinsipidussecondarytocovid19infectionacasereport AT bagherlarijani centraldiabetesinsipidussecondarytocovid19infectionacasereport AT alimosadeghkhah centraldiabetesinsipidussecondarytocovid19infectionacasereport |