Enhanced Effects of Chronic Restraint-Induced Psychological Stress on Total Body Fe-Irradiation-Induced Hematopoietic Toxicity in <i>Trp53</i>-Heterozygous Mice

Enhanced Effects of Chronic Restraint-Induced Psychological Stress on Total Body Fe-Irradiation-Induced Hematopoietic Toxicity in <i>Trp53</i>-Heterozygous Mice

Humans are exposed to both psychological stress (PS) and radiation in some scenarios such as manned deep-space missions. It is of great concern to verify possible enhanced deleterious effects from such concurrent exposure. Pioneer studies showed that chronic restraint-induced PS (CRIPS) could attenu...

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Bibliographic Details
Main Authors: Bing Wang, Takanori Katsube, Kaoru Tanaka, Yasuharu Ninomiya, Hirokazu Hirakawa, Cuihua Liu, Kouichi Maruyama, Guillaume Varès, Seiji Kito, Tetsuo Nakajima, Akira Fujimori, Mitsuru Nenoi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Life
Subjects:
chronic restraint-induced stress
total-body irradiation
iron-particle radiation
peripheral blood hemogram
bone marrow micronucleated erythrocytes
mouse restraint model
Online Access:https://www.mdpi.com/2075-1729/12/4/565

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