Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease

Nutrition and dietary interventions are a central component in the pathophysiology, but also a cornerstone in the management of patients with non-alcoholic fatty liver disease (NAFLD). Summarizing our rapidly advancing understanding of how our diet influences our metabolism and focusing on specific...

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Main Authors: Georg Semmler, Christian Datz, Michael Trauner
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2023-02-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-2022-0364.pdf
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author Georg Semmler
Christian Datz
Michael Trauner
author_facet Georg Semmler
Christian Datz
Michael Trauner
author_sort Georg Semmler
collection DOAJ
description Nutrition and dietary interventions are a central component in the pathophysiology, but also a cornerstone in the management of patients with non-alcoholic fatty liver disease (NAFLD). Summarizing our rapidly advancing understanding of how our diet influences our metabolism and focusing on specific effects on the liver, we provide a comprehensive overview of dietary concepts to counteract the increasing burden of NAFLD. Specifically, we emphasize the importance of dietary calorie restriction independently of the macronutrient composition together with adherence to a Mediterranean diet low in added fructose and processed meat that seems to exert favorable effects beyond calorie restriction. Also, we discuss intermittent fasting as a type of diet specifically tailored to decrease liver fat content and increase ketogenesis, awaiting future study results in NAFLD. Finally, personalized dietary recommendations could be powerful tools to increase the effectiveness of dietary interventions in patients with NAFLD considering the genetic background and the microbiome, among others.
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spelling doaj.art-622e128436e2475f8cfa4effa3314f742023-03-14T01:46:51ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2023-02-0129SupplS244S26010.3350/cmh.2022.03641749Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver diseaseGeorg Semmler0Christian Datz1Michael Trauner2 Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, Oberndorf, Austria Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, AustriaNutrition and dietary interventions are a central component in the pathophysiology, but also a cornerstone in the management of patients with non-alcoholic fatty liver disease (NAFLD). Summarizing our rapidly advancing understanding of how our diet influences our metabolism and focusing on specific effects on the liver, we provide a comprehensive overview of dietary concepts to counteract the increasing burden of NAFLD. Specifically, we emphasize the importance of dietary calorie restriction independently of the macronutrient composition together with adherence to a Mediterranean diet low in added fructose and processed meat that seems to exert favorable effects beyond calorie restriction. Also, we discuss intermittent fasting as a type of diet specifically tailored to decrease liver fat content and increase ketogenesis, awaiting future study results in NAFLD. Finally, personalized dietary recommendations could be powerful tools to increase the effectiveness of dietary interventions in patients with NAFLD considering the genetic background and the microbiome, among others.http://e-cmh.org/upload/pdf/cmh-2022-0364.pdfnafldmediterranean dietintermittent fastingcalorie restricted dietprecision medicine
spellingShingle Georg Semmler
Christian Datz
Michael Trauner
Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
Clinical and Molecular Hepatology
nafld
mediterranean diet
intermittent fasting
calorie restricted diet
precision medicine
title Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
title_full Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
title_fullStr Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
title_full_unstemmed Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
title_short Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
title_sort eating diet and nutrition for the treatment of non alcoholic fatty liver disease
topic nafld
mediterranean diet
intermittent fasting
calorie restricted diet
precision medicine
url http://e-cmh.org/upload/pdf/cmh-2022-0364.pdf
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