Second Wave, Late-Stage Neuroinflammation in Cleared Brains of Aged 5xFAD Alzheimer’s Mice Detected by Macrolaser Light Sheet Microscopy Imaging

Second Wave, Late-Stage Neuroinflammation in Cleared Brains of Aged 5xFAD Alzheimer’s Mice Detected by Macrolaser Light Sheet Microscopy Imaging

This study leverages the innovative imaging capabilities of macrolaser light-sheet microscopy to elucidate the 3D spatial visualization of AD-associated neuropathologic networks in the transparent brains of 44-week-old 5xFAD mice. Brain samples from ten AD and seven control mice were prepared throug...

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Bibliographic Details
Main Authors:	Suk Hyun Lee, Hye Joo Son
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Series:	International Journal of Molecular Sciences
Subjects:	Alzheimer’s disease late-phase neuroinflammation astrogliosis 5xFAD light-sheet microscopy tissue clearing
Online Access:	https://www.mdpi.com/1422-0067/24/23/17058

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