Targeting the Fibroblast Growth Factor Receptor (FGFR) Family in Lung Cancer
Lung cancer is the most common cause of cancer-related deaths globally. Genetic alterations, such as amplifications, mutations and translocations in the fibroblast growth factor receptor (FGFR) family have been found in non-small cell lung cancer (NSCLC) where they have a role in cancer initiation a...
Main Authors: | Laura Pacini, Andrew D. Jenks, Nadia Carvalho Lima, Paul H. Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-05-01
|
Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/10/5/1154 |
Similar Items
-
Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review
by: Jia Zheng, et al.
Published: (2022-04-01) -
Inhibition of the FGF/FGFR System Induces Apoptosis in Lung Cancer Cells via c-Myc Downregulation and Oxidative Stress
by: Arianna Giacomini, et al.
Published: (2020-12-01) -
FGFR-TKI resistance in cancer: current status and perspectives
by: Sitong Yue, et al.
Published: (2021-02-01) -
Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma
by: Michihisa Kono, et al.
Published: (2022-12-01) -
FGFR3-TACCs3 Fusions and Their Clinical Relevance in Human Glioblastoma
by: Hanna Gött, et al.
Published: (2022-08-01)