Induction of broadly neutralising HCV antibodies in mice by integration-deficient lentiviral vector-based pseudotyped particles.

Induction of broadly neutralising HCV antibodies in mice by integration-deficient lentiviral vector-based pseudotyped particles.

INTRODUCTION: Integration-deficient lentiviral vectors (IDLVs) are a promising platform for immunisation to elicit both humoral immunity and cellular mediated immunity (CMI). Here, we compared the specific immunity in mice immunised via different regimens (homologous and cocktail) with IDLV-based HC...

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Bibliographic Details
Main Authors: Yao Deng, Jie Guan, Bo Wen, Na Zhu, Hong Chen, Jindong Song, Yang Yang, Yue Wang, Wenjie Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633868?pdf=render

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http://europepmc.org/articles/PMC3633868?pdf=render

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