An HuR mutant, HuR-V225I, identified in adult T-cell Leukemia/Lymphoma, alters the pro-apoptotic function of HuR

An HuR mutant, HuR-V225I, identified in adult T-cell Leukemia/Lymphoma, alters the pro-apoptotic function of HuR

Abstract The RNA-binding protein HuR regulates various cellular processes, such as proliferation, differentiation, and cell fate. Moreover, recent studies have shown that HuR modulates the expression of factors important for tumor growth and progression. Despite its prominent role in tumorigenesis,...

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Dades bibliogràfiques
Autors principals: Bianca Colalillo, Sujitha Sali, Ali H. Aldouhki, Isabelle Aubry, Sergio Di Marco, Michel L. Tremblay, Imed E. Gallouzi
Format: Article
Idioma:English
Publicat: Nature Publishing Group 2024-12-01
Col·lecció:Cell Death Discovery
Accés en línia:https://doi.org/10.1038/s41420-024-02268-w

Internet

https://doi.org/10.1038/s41420-024-02268-w

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