Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system
Multimodal neuroimaging plays an important role in neuroscience research. Integrated noninvasive neuroimaging modalities, such as magnetoencephalography (MEG), electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS), allow neural activity and related physiological processes in...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | NeuroImage |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811922005377 |
| _version_ | 1828542694393118720 |
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| author | Xingyu Ru Kaiyan He Bingjiang Lyu Dongxu Li Wei Xu Wenyu Gu Xiao Ma Jiayi Liu Congcong Li Tingyue Li Fufu Zheng Xiaozhou Yan Yugang Yin Hongfeng Duan Shuai Na Shuangai Wan Jie Qin Jingwei Sheng Jia-Hong Gao |
| author_facet | Xingyu Ru Kaiyan He Bingjiang Lyu Dongxu Li Wei Xu Wenyu Gu Xiao Ma Jiayi Liu Congcong Li Tingyue Li Fufu Zheng Xiaozhou Yan Yugang Yin Hongfeng Duan Shuai Na Shuangai Wan Jie Qin Jingwei Sheng Jia-Hong Gao |
| author_sort | Xingyu Ru |
| collection | DOAJ |
| description | Multimodal neuroimaging plays an important role in neuroscience research. Integrated noninvasive neuroimaging modalities, such as magnetoencephalography (MEG), electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS), allow neural activity and related physiological processes in the brain to be precisely and comprehensively depicted, providing an effective and advanced platform to study brain function. Noncryogenic optically pumped magnetometer (OPM) MEG has high signal power due to its on-scalp sensor layout and enables more flexible configurations than traditional commercial superconducting MEG. Here, we integrate OPM-MEG with EEG and fNIRS to develop a multimodal neuroimaging system that can simultaneously measure brain electrophysiology and hemodynamics. We conducted a series of experiments to demonstrate the feasibility and robustness of our MEG-EEG-fNIRS acquisition system. The complementary neural and physiological signals simultaneously collected by our multimodal imaging system provide opportunities for a wide range of potential applications in neurovascular coupling, wearable neuroimaging, hyperscanning and brain-computer interfaces. |
| first_indexed | 2024-12-12T02:01:06Z |
| format | Article |
| id | doaj.art-624315a3fc3d48e8b722e6899f76df35 |
| institution | Directory Open Access Journal |
| issn | 1095-9572 |
| language | English |
| last_indexed | 2024-12-12T02:01:06Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj.art-624315a3fc3d48e8b722e6899f76df352022-12-22T00:42:10ZengElsevierNeuroImage1095-95722022-10-01259119420Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition systemXingyu Ru0Kaiyan He1Bingjiang Lyu2Dongxu Li3Wei Xu4Wenyu Gu5Xiao Ma6Jiayi Liu7Congcong Li8Tingyue Li9Fufu Zheng10Xiaozhou Yan11Yugang Yin12Hongfeng Duan13Shuai Na14Shuangai Wan15Jie Qin16Jingwei Sheng17Jia-Hong Gao18Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaChangping Laboratory, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaChangping Laboratory, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaChangping Laboratory, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, ChinaBeijing PsycheArk Science & Technology Development Co., Ltd., Beijing, ChinaBeijing PsycheArk Science & Technology Development Co., Ltd., Beijing, ChinaBeijing PsycheArk Science & Technology Development Co., Ltd., Beijing, ChinaNational Biomedical Imaging Center, Peking University, Beijing, ChinaBeijing Automation Control Equipment Institute, Beijing, ChinaBeijing Automation Control Equipment Institute, Beijing, ChinaBeijing Quanmag Healthcare, Beijing, ChinaBeijing City Key Lab for Medical Physics and Engineering, Institution of Heavy Ion Physics, School of Physics, Peking University, Beijing, China; Changping Laboratory, Beijing, China; National Biomedical Imaging Center, Peking University, Beijing, China; McGovern Institute for Brain Research, Peking University, Beijing, China; Center for MRI Research, Academy for Advance Interdisciplinary Studies, Peking University, Beijing 100871, China; Corresponding author.Multimodal neuroimaging plays an important role in neuroscience research. Integrated noninvasive neuroimaging modalities, such as magnetoencephalography (MEG), electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS), allow neural activity and related physiological processes in the brain to be precisely and comprehensively depicted, providing an effective and advanced platform to study brain function. Noncryogenic optically pumped magnetometer (OPM) MEG has high signal power due to its on-scalp sensor layout and enables more flexible configurations than traditional commercial superconducting MEG. Here, we integrate OPM-MEG with EEG and fNIRS to develop a multimodal neuroimaging system that can simultaneously measure brain electrophysiology and hemodynamics. We conducted a series of experiments to demonstrate the feasibility and robustness of our MEG-EEG-fNIRS acquisition system. The complementary neural and physiological signals simultaneously collected by our multimodal imaging system provide opportunities for a wide range of potential applications in neurovascular coupling, wearable neuroimaging, hyperscanning and brain-computer interfaces.http://www.sciencedirect.com/science/article/pii/S1053811922005377MagnetoencephalographyOptically pumped magnetometerElectroencephalographyFunctional near-infrared spectroscopyMultimodal neuroimaging |
| spellingShingle | Xingyu Ru Kaiyan He Bingjiang Lyu Dongxu Li Wei Xu Wenyu Gu Xiao Ma Jiayi Liu Congcong Li Tingyue Li Fufu Zheng Xiaozhou Yan Yugang Yin Hongfeng Duan Shuai Na Shuangai Wan Jie Qin Jingwei Sheng Jia-Hong Gao Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system NeuroImage Magnetoencephalography Optically pumped magnetometer Electroencephalography Functional near-infrared spectroscopy Multimodal neuroimaging |
| title | Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system |
| title_full | Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system |
| title_fullStr | Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system |
| title_full_unstemmed | Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system |
| title_short | Multimodal neuroimaging with optically pumped magnetometers: A simultaneous MEG-EEG-fNIRS acquisition system |
| title_sort | multimodal neuroimaging with optically pumped magnetometers a simultaneous meg eeg fnirs acquisition system |
| topic | Magnetoencephalography Optically pumped magnetometer Electroencephalography Functional near-infrared spectroscopy Multimodal neuroimaging |
| url | http://www.sciencedirect.com/science/article/pii/S1053811922005377 |
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