AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway.
During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called "dauer." During this stage, the germline stem cells (GSCs) become quiescent in an AMP-activated Protein Kinase (AMPK)-dependent manner, and in the absence of AMPK, the GSCs overp...
| Hlavní autoři: | , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Public Library of Science (PLoS)
2019-06-01
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| Edice: | PLoS Biology |
| On-line přístup: | https://doi.org/10.1371/journal.pbio.3000309 |