Epilepsy in patients with supratentorial meningiomas
Meningiomas are the most common primary intracranial tumors. They are mostly slow-growing and of benign histopathology rendering them curable by surgery alone. Symptomatic lesions depend on the location with signs of focal neurological deficits or increased intracranial pressure. Seizures are the pr...
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| Format: | Article |
| Language: | English |
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University of Belgrade, Medical Faculty
2023-01-01
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| Series: | Medicinski Podmladak |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2023/0369-15272305009B.pdf |
| _version_ | 1827293591412670464 |
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| author | Bogdanović Ivan Ristić Aleksandar Grujičić Danica |
| author_facet | Bogdanović Ivan Ristić Aleksandar Grujičić Danica |
| author_sort | Bogdanović Ivan |
| collection | DOAJ |
| description | Meningiomas are the most common primary intracranial tumors. They are mostly slow-growing and of benign histopathology rendering them curable by surgery alone. Symptomatic lesions depend on the location with signs of focal neurological deficits or increased intracranial pressure. Seizures are the presenting symptoms in approximately 30% of supratentorial meningiomas. Epileptogenesis in these patients is not yet clearly defined. Epilepsy negatively affects the quality of life, limits independence, and impairs cognition, as well as increases the risk for psychiatric comorbidities including depression. Although surgical resection may offer seizure freedom in more than 60% of meningiomas, seizures persist after surgical resection in a significant number of patients. The potential preoperative and postoperative predictors for seizures in meningioma patients have been analyzed in multiple studies. Antiseizure medications are employed in the treatment of these patients, however, their application is often followed by adverse neurocognitive side effects and inefficacy in some patients. Understanding various clinical, histopathological, and surgical factors potentially associated with epilepsy can help guide more effective seizure control and allow for better assessment of risk before and after surgery. Patients with persistent seizures may benefit from referral to an epilepsy center for evaluation. |
| first_indexed | 2024-04-24T13:41:45Z |
| format | Article |
| id | doaj.art-624a1fdb67834ef0961cb918d3f0318f |
| institution | Directory Open Access Journal |
| issn | 0369-1527 2466-5525 |
| language | English |
| last_indexed | 2024-04-24T13:41:45Z |
| publishDate | 2023-01-01 |
| publisher | University of Belgrade, Medical Faculty |
| record_format | Article |
| series | Medicinski Podmladak |
| spelling | doaj.art-624a1fdb67834ef0961cb918d3f0318f2024-04-04T08:28:43ZengUniversity of Belgrade, Medical FacultyMedicinski Podmladak0369-15272466-55252023-01-0174591310.5937/mp74-430840369-15272305009BEpilepsy in patients with supratentorial meningiomasBogdanović Ivan0https://orcid.org/0000-0003-0055-5201Ristić Aleksandar1https://orcid.org/0000-0002-7564-1641Grujičić Danica2https://orcid.org/0000-0002-1634-3898Univerzitet u Beogradu, Medicinski fakultet, Beograd, SerbiaUniverzitet u Beogradu, Medicinski fakultet, Beograd, SerbiaUniverzitet u Beogradu, Medicinski fakultet, Beograd, SerbiaMeningiomas are the most common primary intracranial tumors. They are mostly slow-growing and of benign histopathology rendering them curable by surgery alone. Symptomatic lesions depend on the location with signs of focal neurological deficits or increased intracranial pressure. Seizures are the presenting symptoms in approximately 30% of supratentorial meningiomas. Epileptogenesis in these patients is not yet clearly defined. Epilepsy negatively affects the quality of life, limits independence, and impairs cognition, as well as increases the risk for psychiatric comorbidities including depression. Although surgical resection may offer seizure freedom in more than 60% of meningiomas, seizures persist after surgical resection in a significant number of patients. The potential preoperative and postoperative predictors for seizures in meningioma patients have been analyzed in multiple studies. Antiseizure medications are employed in the treatment of these patients, however, their application is often followed by adverse neurocognitive side effects and inefficacy in some patients. Understanding various clinical, histopathological, and surgical factors potentially associated with epilepsy can help guide more effective seizure control and allow for better assessment of risk before and after surgery. Patients with persistent seizures may benefit from referral to an epilepsy center for evaluation.https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2023/0369-15272305009B.pdfepilepsymeningiomatumorpredictorssurgery |
| spellingShingle | Bogdanović Ivan Ristić Aleksandar Grujičić Danica Epilepsy in patients with supratentorial meningiomas Medicinski Podmladak epilepsy meningioma tumor predictors surgery |
| title | Epilepsy in patients with supratentorial meningiomas |
| title_full | Epilepsy in patients with supratentorial meningiomas |
| title_fullStr | Epilepsy in patients with supratentorial meningiomas |
| title_full_unstemmed | Epilepsy in patients with supratentorial meningiomas |
| title_short | Epilepsy in patients with supratentorial meningiomas |
| title_sort | epilepsy in patients with supratentorial meningiomas |
| topic | epilepsy meningioma tumor predictors surgery |
| url | https://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2023/0369-15272305009B.pdf |
| work_keys_str_mv | AT bogdanovicivan epilepsyinpatientswithsupratentorialmeningiomas AT risticaleksandar epilepsyinpatientswithsupratentorialmeningiomas AT grujicicdanica epilepsyinpatientswithsupratentorialmeningiomas |