Heat-Stable Enterotoxin Secretions Assessed via ICP-MS Reveal Iron-Mediated Regulation of Virulence in CFA/I- and CS6-Expressing ETEC Isolates

Heat-Stable Enterotoxin Secretions Assessed via ICP-MS Reveal Iron-Mediated Regulation of Virulence in CFA/I- and CS6-Expressing ETEC Isolates

Enterotoxigenic <i>Escherichia coli</i> (ETEC) are a significant cause of childhood diarrhea in low-resource settings. ETEC are defined by the production of heat-stable enterotoxin (ST) and/or heat-labile enterotoxin (LT), which alter intracellular cyclic nucleotide signaling and cause t...

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Bibliographic Details
Main Authors: Ian E. Hollifield, Natalya I. Motyka, Sydney R. Stewart, Michelle D. Blyth, Kaylynn A. Fernando, Kristen L. Clement, Jacob P. Bitoun
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
enterotoxins
diarrhea
ETEC
secretion
metals
adhesin
Online Access:https://www.mdpi.com/2073-4409/12/4/567

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