Non-Anticoagulant Heparan Sulfate from the Ascidian <em>Phallusia nigra</em> Prevents Colon Carcinoma Metastasis in Mice by Disrupting Platelet-Tumor Cell Interaction
Although metastasis is the primary cause of death in patients with malignant solid tumors, efficient anti-metastatic therapies are not clinically available currently. Sulfated glycosaminoglycans from marine sources have shown promising pharmacological effects, acting on different steps of the metast...
Main Authors: | Christiane F. S. Silva, Juliana M. Motta, Felipe C. O. B. Teixeira, Angélica M. Gomes, Eduardo Vilanova, Eliene O. Kozlowski, Lubor Borsig, Mauro S. G. Pavão |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/6/1353 |
Similar Items
-
Mesenchymal Characteristics and Predictive Biomarkers on Circulating Tumor Cells for Therapeutic Strategy
by: Takahiro Okabe, et al.
Published: (2020-11-01) -
Circulating Tumor Cell Clusters: United We Stand Divided We Fall
by: Samuel Amintas, et al.
Published: (2020-04-01) -
Is platelet-lymphocyte ratio (PLR) a predictor of thrombosis and together with circulating tumor cells capable to determine recurrence-free survival in patients with gastric cancer?
by: Bruno Soriano Pignataro, et al.
Published: (2022-10-01) -
Circulating Tumor Cells from Enumeration to Analysis: Current Challenges and Future Opportunities
by: Yu-Ping Yang, et al.
Published: (2021-05-01) -
Circulating Tumor Cells Detection and Counting in Uveal Melanomas by a Filtration-Based Method
by: Cinzia Mazzini, et al.
Published: (2014-02-01)