Renal function and chronic heart failure treatment effectiveness in the elderly
The article is devoted to the association between long-term chronic heart failure (CHF) treatment and renal function in elderly patients. In total, 80 individuals aged 62-86 years were examined at Day 15-30 after myocardial infarction complicated by CHF. All participants received standard CHF treatm...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2007-04-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2072 |
| Summary: | The article is devoted to the association between long-term chronic heart failure (CHF) treatment and renal function in elderly patients. In total, 80 individuals aged 62-86 years were examined at Day 15-30 after myocardial infarction complicated by CHF. All participants received standard CHF treatment. At baseline, 3 and 12 months later, all patients underwent clinical examination, with CHF functional class (FC) identification, echocardiography, renal function and heart rate variability (HRV) measurement. Two groups were identified: Group 1 (n=51), with nephroprotective effect observed, according to glomerular filtration rate (GFR) and microalbuminuria (MA) data; Group 2 (n=29), with nephronegative effect of CHF therapy, manifested in deteriorated GFR and MA parameters. In patients with MI and CHF, renal dysfunction predicted poor cardiovascular prognosis. CHF therapy effectiveness in the elderly was influenced by nephrotropic action of basic treatment. Decreased or disappeared MA, normalized GFR by the end of Week 12 predicted good or satisfactory clinical effects. |
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| ISSN: | 1560-4071 2618-7620 |