Detection of live M. bovis BCG in tissues and IFN-γ responses in European badgers (Meles meles) vaccinated by oropharyngeal instillation or directly in the ileum

Detection of live M. bovis BCG in tissues and IFN-γ responses in European badgers (Meles meles) vaccinated by oropharyngeal instillation or directly in the ileum

Abstract Background Oral vaccination with Mycobacterium bovis Bacille of Calmette and Guerin (BCG) has provided protection against M. bovis to badgers both experimentally and in the field. There is also evidence suggesting that the persistence of live BCG within the host is important for maintaining...

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Bibliographic Details
Main Authors: Sandrine Lesellier, Maria-Laura Boschiroli, Jacques Barrat, Christoph Wanke, Francisco J. Salguero, Waldo L. Garcia-Jimenez, Alex Nunez, Ana Godinho, John Spiropoulos, Simonette Palmer, Dipesh Dave, Paul Anderson, Jean-Marc Boucher, Krystel de Cruz, Sylvie Henault, Lorraine Michelet, Sonya Gowtage, Gareth A. Williams, Allan K. Nadian, Elodie Monchâtre-Leroy, Frank Boué, Mark A. Chambers, Céline Richomme
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Veterinary Research
Subjects:
BCG
Badger
Vaccine
Mucosa
Capsule
Tonsil
Online Access:https://doi.org/10.1186/s12917-019-2166-4

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