Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts

Wnt Signaling Is Deranged in Asthmatic Bronchial Epithelium and Fibroblasts

Both canonical and non-canonical Wnt signaling pathway alterations have been documented in pulmonary disease pathogenesis and progression; therefore, they can be an attractive target for pharmaceutical management of severe asthma. Wnt/β-catenin signaling was shown to link early embryonic lung develo...

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Bibliographic Details
Main Authors: Mahmood Yaseen Hachim, Noha Mousaad Elemam, Rakhee K. Ramakrishnan, Khuloud Bajbouj, Ronald Olivenstein, Ibrahim Yaseen Hachim, Saba Al Heialy, Qutayba Hamid, Hauke Busch, Rifat Hamoudi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
asthma
Wnt/b-catenin
remodeling
in silco analysis
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.641404/full

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