Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy

The paper reviews an update on the possibilities of providing care for patients with spontaneous non-traumatic intracranial hemorrhage (ICH) developing in patients with atrial fibrillation who use oral anticoagulants. The incidence of ICH is shown to be considerably lower when nonvitamin K-dependent...

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Main Author: S. N. Yanishevsky
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2019-06-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/1138
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author S. N. Yanishevsky
author_facet S. N. Yanishevsky
author_sort S. N. Yanishevsky
collection DOAJ
description The paper reviews an update on the possibilities of providing care for patients with spontaneous non-traumatic intracranial hemorrhage (ICH) developing in patients with atrial fibrillation who use oral anticoagulants. The incidence of ICH is shown to be considerably lower when nonvitamin K-dependent anticoagulants (NOACs) are used, but the hematoma evolution scenarios do not differ between the groups of patients receiving vitamin K antagonists or NOACs. The results of studies assessing hypertension therapy in patients with ICH are compared. The possibilities of using various reversal agents for various oral anticoagulants are also discussed. Since one of the main problems associated with increased mortality and severe disabilities is the progression rate of ICH, the possibility of using a specific antagonist can determine the choice of an anticoagulant for the primary prevention of ischemic stroke in a patient with atrial fibrillation.
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spelling doaj.art-62685ae12aa64e83b45b050dcda5c5fc2024-10-17T16:15:26ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422019-06-01113S828810.14412/2074-2711-2019-3S-82-88881Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapyS. N. Yanishevsky0S.M. Kirov Military Medical AcademyThe paper reviews an update on the possibilities of providing care for patients with spontaneous non-traumatic intracranial hemorrhage (ICH) developing in patients with atrial fibrillation who use oral anticoagulants. The incidence of ICH is shown to be considerably lower when nonvitamin K-dependent anticoagulants (NOACs) are used, but the hematoma evolution scenarios do not differ between the groups of patients receiving vitamin K antagonists or NOACs. The results of studies assessing hypertension therapy in patients with ICH are compared. The possibilities of using various reversal agents for various oral anticoagulants are also discussed. Since one of the main problems associated with increased mortality and severe disabilities is the progression rate of ICH, the possibility of using a specific antagonist can determine the choice of an anticoagulant for the primary prevention of ischemic stroke in a patient with atrial fibrillation.https://nnp.ima-press.net/nnp/article/view/1138atrial fibrillationstroke preventionintracranial hemorrhageoral anticoagulantsnew oral anticoagulantsdirect oral anticoagulantsvitamin k antagonistsspecific antagonistdabigatranidarucizumab
spellingShingle S. N. Yanishevsky
Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
Неврология, нейропсихиатрия, психосоматика
atrial fibrillation
stroke prevention
intracranial hemorrhage
oral anticoagulants
new oral anticoagulants
direct oral anticoagulants
vitamin k antagonists
specific antagonist
dabigatran
idarucizumab
title Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
title_full Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
title_fullStr Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
title_full_unstemmed Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
title_short Intracranial hemorrhage in patients taking oral anticoagulants. Current possibilities for therapy
title_sort intracranial hemorrhage in patients taking oral anticoagulants current possibilities for therapy
topic atrial fibrillation
stroke prevention
intracranial hemorrhage
oral anticoagulants
new oral anticoagulants
direct oral anticoagulants
vitamin k antagonists
specific antagonist
dabigatran
idarucizumab
url https://nnp.ima-press.net/nnp/article/view/1138
work_keys_str_mv AT snyanishevsky intracranialhemorrhageinpatientstakingoralanticoagulantscurrentpossibilitiesfortherapy