A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies

A comparison of existing global DNA methylation assays to low-coverage whole-genome bisulfite sequencing for epidemiological studies

DNA methylation is an epigenetic mark at the interface of genetic and environmental factors relevant to human disease. Quantitative assessments of global DNA methylation levels have therefore become important tools in epidemiology research, particularly for understanding effects of environmental exp...

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Bibliographic Details
Main Authors:	Florence K. Crary-Dooley, Mitchell E. Tam, Keith W. Dunaway, Irva Hertz-Picciotto, Rebecca J. Schmidt, Janine M. LaSalle
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-03-01
Series:	Epigenetics
Subjects:	environmental epigenetics global dna methylation pyrosequencing whole-genome bisulfite sequencing
Online Access:	http://dx.doi.org/10.1080/15592294.2016.1276680

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