Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models

Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models

Abstract Malaria can have severe long-term effects. Even after treatment with antimalarial drugs eliminates the parasite, survivors of cerebral malaria may suffer from irreversible brain damage, leading to cognitive deficits. Angiotensin II, a natural human peptide hormone that regulates blood press...

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Bibliographic Details
Main Authors: Adriana F. Silva, Marcelo D. T. Torres, Leandro S. Silva, Flavio L. Alves, Antonio Miranda, Vani X. Oliveira, Cesar de la Fuente-Nunez, Ana Acacia S. Pinheiro
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51267-5

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