Eukarion-134 Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Dysfunction in Human Skeletal Muscle Cells

Eukarion-134 Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Dysfunction in Human Skeletal Muscle Cells

Maladaptive endoplasmic reticulum (ER) stress is associated with modified reactive oxygen species (ROS) generation and mitochondrial abnormalities; and is postulated as a potential mechanism involved in muscle weakness in myositis, an acquired autoimmune neuromuscular disease. This study investigate...

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Bibliographic Details
Main Authors: Anastasia Thoma, Max Lyon, Nasser Al-Shanti, Gareth A. Nye, Robert G. Cooper, Adam P. Lightfoot
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
ER stress
mitochondria
reactive oxygen species
antioxidant
EUK-134
Online Access:https://www.mdpi.com/2076-3921/9/8/710

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