The role of ozone treatment as integrative medicine. An evidence and gap map

IntroductionThe Brazil has one of the largest public health systems in the world and in the 1980's, Traditional, Complementary and Integrative Medicine were introduced. In 2018, the treatment with ozone became a complementary integrative practice showing several benefits. However, its effective...

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Main Authors: Maria Emilia Gadelha Serra, José Baeza-Noci, Carmen Verônica Mendes Abdala, Marilia Moura Luvisotto, Charise Dallazem Bertol, Ana Paula Anzolin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.1112296/full
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author Maria Emilia Gadelha Serra
José Baeza-Noci
Carmen Verônica Mendes Abdala
Marilia Moura Luvisotto
Charise Dallazem Bertol
Ana Paula Anzolin
author_facet Maria Emilia Gadelha Serra
José Baeza-Noci
Carmen Verônica Mendes Abdala
Marilia Moura Luvisotto
Charise Dallazem Bertol
Ana Paula Anzolin
author_sort Maria Emilia Gadelha Serra
collection DOAJ
description IntroductionThe Brazil has one of the largest public health systems in the world and in the 1980's, Traditional, Complementary and Integrative Medicine were introduced. In 2018, the treatment with ozone became a complementary integrative practice showing several benefits. However, its effectiveness needs to be researched. The objective of this evidence gap map is to describe contributions of Integrative Medicines-Ozone treatment in different clinical conditions, to promote evidence-based practice.MethodsWe applied the methodology developed by Latin American and Caribbean Center on Health Sciences Information based on the 3iE evidence gap map. The EMBASE, PubMed and Virtual Health Library databases, using the MeSH and DeCS terms for the treatment with Ozone were used.Results26 systematic reviews were characterized, distributed in a matrix containing 6 interventions (parenteral oxygen/ozone gas mixture; parenteral ozonated water; systemic routes; topical application ozonated water; topical oxygen/ozone gas mixture; and topical ozonated oil) and 55 outcomes (cancer, infection, inflammation, pain, quality of life, wound healing and adverse effects). 334 associations between intervention and outcome were observed, emphasizing the parenteral oxygen/ozone gas mixture intervention (192 associations, 57%).ConclusionsThe evidence gap map presents an overview of contributions of Ozone treatment in controlling pain, infections, inflammation and wound healing, as well as increasing the quality of life, and it is directed to researchers and health professionals specialized in Ozone treatment. No serious adverse effects were related. Therefore, this treatment may be even more widely known as an integrative treatment, considering its low cost, efficiency and safety. Future studies should adopt economic impact assessments and the organization of health services.
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spelling doaj.art-6279da9358944f64b99c157acd502c432023-01-16T05:09:24ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-01-011010.3389/fpubh.2022.11122961112296The role of ozone treatment as integrative medicine. An evidence and gap mapMaria Emilia Gadelha Serra0José Baeza-Noci1Carmen Verônica Mendes Abdala2Marilia Moura Luvisotto3Charise Dallazem Bertol4Ana Paula Anzolin5Brazilian Society of Medical Ozone Therapy (SOBOM), São Paulo, BrazilWorld Federation of Ozone Therapy (WFOT), Brescia, ItalyLatin American and Caribbean Center on Health Sciences (BIREME/OPAS/OMS), São Paulo, BrazilBrazilian Society of Medical Ozone Therapy (SOBOM), São Paulo, BrazilBrazilian Society of Medical Ozone Therapy (SOBOM), São Paulo, BrazilBrazilian Society of Medical Ozone Therapy (SOBOM), São Paulo, BrazilIntroductionThe Brazil has one of the largest public health systems in the world and in the 1980's, Traditional, Complementary and Integrative Medicine were introduced. In 2018, the treatment with ozone became a complementary integrative practice showing several benefits. However, its effectiveness needs to be researched. The objective of this evidence gap map is to describe contributions of Integrative Medicines-Ozone treatment in different clinical conditions, to promote evidence-based practice.MethodsWe applied the methodology developed by Latin American and Caribbean Center on Health Sciences Information based on the 3iE evidence gap map. The EMBASE, PubMed and Virtual Health Library databases, using the MeSH and DeCS terms for the treatment with Ozone were used.Results26 systematic reviews were characterized, distributed in a matrix containing 6 interventions (parenteral oxygen/ozone gas mixture; parenteral ozonated water; systemic routes; topical application ozonated water; topical oxygen/ozone gas mixture; and topical ozonated oil) and 55 outcomes (cancer, infection, inflammation, pain, quality of life, wound healing and adverse effects). 334 associations between intervention and outcome were observed, emphasizing the parenteral oxygen/ozone gas mixture intervention (192 associations, 57%).ConclusionsThe evidence gap map presents an overview of contributions of Ozone treatment in controlling pain, infections, inflammation and wound healing, as well as increasing the quality of life, and it is directed to researchers and health professionals specialized in Ozone treatment. No serious adverse effects were related. Therefore, this treatment may be even more widely known as an integrative treatment, considering its low cost, efficiency and safety. Future studies should adopt economic impact assessments and the organization of health services.https://www.frontiersin.org/articles/10.3389/fpubh.2022.1112296/fullsystematic reviewsOzone TherapyMedical Ozone Therapyevidence gap mapcomplementary therapies
spellingShingle Maria Emilia Gadelha Serra
José Baeza-Noci
Carmen Verônica Mendes Abdala
Marilia Moura Luvisotto
Charise Dallazem Bertol
Ana Paula Anzolin
The role of ozone treatment as integrative medicine. An evidence and gap map
Frontiers in Public Health
systematic reviews
Ozone Therapy
Medical Ozone Therapy
evidence gap map
complementary therapies
title The role of ozone treatment as integrative medicine. An evidence and gap map
title_full The role of ozone treatment as integrative medicine. An evidence and gap map
title_fullStr The role of ozone treatment as integrative medicine. An evidence and gap map
title_full_unstemmed The role of ozone treatment as integrative medicine. An evidence and gap map
title_short The role of ozone treatment as integrative medicine. An evidence and gap map
title_sort role of ozone treatment as integrative medicine an evidence and gap map
topic systematic reviews
Ozone Therapy
Medical Ozone Therapy
evidence gap map
complementary therapies
url https://www.frontiersin.org/articles/10.3389/fpubh.2022.1112296/full
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