Seroprevalence of Hepatitis B Infection among Pregnant Women in One of the Institute of Northern India
Introduction: Hepatitis B Virus (HBV) occurs worldwide with more than 2 billion people being infected with HBV at some time in their lives. Transmission of HBV from carrier mothers to babies can occur during perinatal period and is important factor in determining the prevalence of infection in h...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/8299/20614_CE[Ra1]_F(GH)_PF1(ROAK)_PFA(AK)_PF2(PAG).pdf |
| Summary: | Introduction: Hepatitis B Virus (HBV) occurs worldwide with
more than 2 billion people being infected with HBV at some
time in their lives. Transmission of HBV from carrier mothers to
babies can occur during perinatal period and is important factor
in determining the prevalence of infection in highly endemic
areas.
Aim: To assess the prevalence of hepatitis B infection, among
otherwise healthy pregnant females.
Materials and Methods: This retrospective study analysed
records of antenatal care registry from 1st April 2013 to 30th
March 2014 at our institution. Details of a total of 3686 pregnant
women subjected to screening of Hepatitis B surface antigen
(HBsAg) using Enzyme Linked Immunosorbent Assay (ELISA)
was recorded into a preset proforma. Data thus obtained has
been analysed using SPSS version 13 and presented.
Results: Seroprevalence of HBsAg positive antenatal females
was 1.11%. The mean age of HBsAg positive pregnant women
was 24.98±4.16 years. Thirty one (75.61%) subjects hailed form
a rural area. 4 (09.75%) and 3 (07.31%) subjects had HBV-HCV
co-infection and HBV-HIV co-infection respectively. Mean parity
of women with HBV infection was 1.83±0.87. Most common
age group with HBV infection was 25–30 years.
Conclusion: Around 130 countries in the world are currently
covered by routine hepatitis B immunization. High prevalence of
seropositivity of HBsAg among antenatal female calls for routine
vaccination against HBV infection. Universal free screening for
HBV infection needs to be offered to all antenatal females on an
opt-out basis to prevent the next generation from being grappled
by chronic hepatitis, cirrhosis and hepatocellular carcinoma. |
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| ISSN: | 2249-782X 0973-709X |