Contact allergy to preservatives in Taiwan between 1996 and 2015
Background: Preservatives are widely used in personal and industrial products. Frequent and sustained exposure to preservatives can cause contact allergy. Objective: We investigated the prevalence of contact allergic reactions to common preservatives in Taiwan over a 20-year period. Methods: A retro...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
|
| Series: | Dermatologica Sinica |
| Subjects: | |
| Online Access: | http://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=3;spage=123;epage=128;aulast=Huang |
| _version_ | 1818766379092803584 |
|---|---|
| author | Yen-Kai Huang Yu-Hung Wu Po-Hsuan Lu Mei-Eng Tu |
| author_facet | Yen-Kai Huang Yu-Hung Wu Po-Hsuan Lu Mei-Eng Tu |
| author_sort | Yen-Kai Huang |
| collection | DOAJ |
| description | Background: Preservatives are widely used in personal and industrial products. Frequent and sustained exposure to preservatives can cause contact allergy. Objective: We investigated the prevalence of contact allergic reactions to common preservatives in Taiwan over a 20-year period. Methods: A retrospective analysis was conducted among patients with allergic contact dermatitis who underwent patch testing at our clinic between 1996 and 2015. Patients who showed positive reactions to preservatives were enrolled. The location of the reaction, likely source of the allergen, and patient occupation, sex, and age were recorded. Thirteen common preservatives, including methylchloroisothiazolinone/methylisothiazolinone (MCI/MI), MI, formaldehyde (FA), paraben mix, and quaternium-15, were investigated. Results: Of 757 enrolled patients, 151 showed at least one positive reaction to preservatives. Allergy to MCI/MI (12.5%), the most frequent allergen in the standard series, showed a steeply increasing trend over time. FA (4.8%) and paraben mix (2.1%) were the next common allergens. Cosmetic products were the most common source of exposure (63.6%), while hairdressers and massage therapists were most commonly associated with occupational contact dermatitis. A sharp increase of sensitivity to MCI/MI was observed after 2006 and that of allergy to MI after 2013. Conclusions: In Taiwan, the prevalence of contact allergy to MCI/MI, MI, and parabens has increased in recent years. Individuals who are frequently exposed to cosmetic products should consider precautions against sensitization. |
| first_indexed | 2024-12-18T08:33:03Z |
| format | Article |
| id | doaj.art-627d064ea0cc4ba9abb345cb9532e3a1 |
| institution | Directory Open Access Journal |
| issn | 1027-8117 2223-330X |
| language | English |
| last_indexed | 2024-12-18T08:33:03Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dermatologica Sinica |
| spelling | doaj.art-627d064ea0cc4ba9abb345cb9532e3a12022-12-21T21:14:24ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172223-330X2019-01-0137312312810.4103/ds.ds_21_18Contact allergy to preservatives in Taiwan between 1996 and 2015Yen-Kai HuangYu-Hung WuPo-Hsuan LuMei-Eng TuBackground: Preservatives are widely used in personal and industrial products. Frequent and sustained exposure to preservatives can cause contact allergy. Objective: We investigated the prevalence of contact allergic reactions to common preservatives in Taiwan over a 20-year period. Methods: A retrospective analysis was conducted among patients with allergic contact dermatitis who underwent patch testing at our clinic between 1996 and 2015. Patients who showed positive reactions to preservatives were enrolled. The location of the reaction, likely source of the allergen, and patient occupation, sex, and age were recorded. Thirteen common preservatives, including methylchloroisothiazolinone/methylisothiazolinone (MCI/MI), MI, formaldehyde (FA), paraben mix, and quaternium-15, were investigated. Results: Of 757 enrolled patients, 151 showed at least one positive reaction to preservatives. Allergy to MCI/MI (12.5%), the most frequent allergen in the standard series, showed a steeply increasing trend over time. FA (4.8%) and paraben mix (2.1%) were the next common allergens. Cosmetic products were the most common source of exposure (63.6%), while hairdressers and massage therapists were most commonly associated with occupational contact dermatitis. A sharp increase of sensitivity to MCI/MI was observed after 2006 and that of allergy to MI after 2013. Conclusions: In Taiwan, the prevalence of contact allergy to MCI/MI, MI, and parabens has increased in recent years. Individuals who are frequently exposed to cosmetic products should consider precautions against sensitization.http://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=3;spage=123;epage=128;aulast=HuangContact dermatitismethylchloroisothiazolinonemethylisothiazolinoneparabenspreservatives |
| spellingShingle | Yen-Kai Huang Yu-Hung Wu Po-Hsuan Lu Mei-Eng Tu Contact allergy to preservatives in Taiwan between 1996 and 2015 Dermatologica Sinica Contact dermatitis methylchloroisothiazolinone methylisothiazolinone parabens preservatives |
| title | Contact allergy to preservatives in Taiwan between 1996 and 2015 |
| title_full | Contact allergy to preservatives in Taiwan between 1996 and 2015 |
| title_fullStr | Contact allergy to preservatives in Taiwan between 1996 and 2015 |
| title_full_unstemmed | Contact allergy to preservatives in Taiwan between 1996 and 2015 |
| title_short | Contact allergy to preservatives in Taiwan between 1996 and 2015 |
| title_sort | contact allergy to preservatives in taiwan between 1996 and 2015 |
| topic | Contact dermatitis methylchloroisothiazolinone methylisothiazolinone parabens preservatives |
| url | http://www.dermsinica.org/article.asp?issn=1027-8117;year=2019;volume=37;issue=3;spage=123;epage=128;aulast=Huang |
| work_keys_str_mv | AT yenkaihuang contactallergytopreservativesintaiwanbetween1996and2015 AT yuhungwu contactallergytopreservativesintaiwanbetween1996and2015 AT pohsuanlu contactallergytopreservativesintaiwanbetween1996and2015 AT meiengtu contactallergytopreservativesintaiwanbetween1996and2015 |