Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou
AIM: To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs. METHODS: The clinical data of 155 patients were retrospectively collected in this study, and the pathogenic bacteria species and drug resistance of each...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2024-04-01
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| Series: | International Journal of Ophthalmology |
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| Online Access: | http://ies.ijo.cn/en_publish/2024/4/20240414.pdf |
| _version_ | 1797244629332000768 |
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| author | Li Zhang Hai-Zhang You Guo-Hui Wang Wei Xu Jian-Shan Li Qing-Liang Zhao Shu Du |
| author_facet | Li Zhang Hai-Zhang You Guo-Hui Wang Wei Xu Jian-Shan Li Qing-Liang Zhao Shu Du |
| author_sort | Li Zhang |
| collection | DOAJ |
| description | AIM: To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs. METHODS: The clinical data of 155 patients were retrospectively collected in this study, and the pathogenic bacteria species and drug resistance of each pathogenic bacteria were analyzed. RESULTS: Among the 155 patients (age from 12 to 87 years old, with an average age of 57, 99 males and 56 females) with eye infections (160 eyes: 74 in the left eye, 76 in the right eye and 5 in both eyes, all of which were exogenous), 71 (45.81%) strains were gram-positive bacteria, 23 (14.84%) strains were gram-negative bacteria and 61 (39.35%) strains were fungi. Gram-positive bacteria were highly resistant to penicillin and erythromycin (78.87% and 46.48% respectively), but least resistant to vancomycin at 0. Gram-negative bacteria were highly resistant to cefoxitin and compound sulfamethoxazole (100% and 95.65% respectively), but least resistant to meropenem at 0. Comparison of the resistance of gram-positive and gram-negative bacteria to some drugs revealed statistically significant differences (P<0.05) in the resistance of both to cefoxitin, cotrimoxazole, levofloxacin, cefuroxime, ceftriaxone and ceftazidime, and both had higher rates of resistance to gram-negative bacteria than to gram-positive bacteria. The distribution of bacterial infection strains showed that Staphylococcus epidermidis was the most common strain in the conjunctiva, cornea, aqueous humor or vitreous body and other eye parts. Besides, Fusarium and Pseudomonas aeruginosa were also among the most common strains of conjunctival and corneal infections. CONCLUSION: Gram-positive bacteria are the dominant bacteria in eye infections, followed by gram-negative bacteria and fungi. Considering the resistance of gram-negative bacteria to multiple drugs, monitoring of bacteria should be strengthened in eye bacterial infections for effective prevention and control to reduce complications caused by eye infections. |
| first_indexed | 2024-04-24T19:14:03Z |
| format | Article |
| id | doaj.art-62812209dbe24bf1baae5affb4d22a04 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-04-24T19:14:03Z |
| publishDate | 2024-04-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-62812209dbe24bf1baae5affb4d22a042024-03-26T08:43:46ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982024-04-0117470070610.18240/ijo.2024.04.1420240414Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in SuzhouLi Zhang0Hai-Zhang You1Guo-Hui Wang2Wei Xu3Jian-Shan Li4Qing-Liang Zhao5Shu Du6Li Zhang. Department of Hospital-Acquired Infection Control, Lixiang Eye Hospital of Soochow University, No.200 of East Ganjiang Road, Gusu District, Suzhou 215021, Jiangsu Province, China. zhang3036_li@163.comDepartment of Administrative Office, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaDepartment of Clinical Laboratory, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaDepartment of Clinical Laboratory, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaDepartment of Pharmacy, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaDepartment of Corneal and Lacrimal Passage, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaDepartment of Fundus Diseases and Ocular Trauma, Lixiang Eye Hospital of Soochow University, Suzhou 215021, Jiangsu Province, ChinaAIM: To investigate the types of bacteria in patients with eye infections in Suzhou and their drug resistance to commonly used antibacterial drugs. METHODS: The clinical data of 155 patients were retrospectively collected in this study, and the pathogenic bacteria species and drug resistance of each pathogenic bacteria were analyzed. RESULTS: Among the 155 patients (age from 12 to 87 years old, with an average age of 57, 99 males and 56 females) with eye infections (160 eyes: 74 in the left eye, 76 in the right eye and 5 in both eyes, all of which were exogenous), 71 (45.81%) strains were gram-positive bacteria, 23 (14.84%) strains were gram-negative bacteria and 61 (39.35%) strains were fungi. Gram-positive bacteria were highly resistant to penicillin and erythromycin (78.87% and 46.48% respectively), but least resistant to vancomycin at 0. Gram-negative bacteria were highly resistant to cefoxitin and compound sulfamethoxazole (100% and 95.65% respectively), but least resistant to meropenem at 0. Comparison of the resistance of gram-positive and gram-negative bacteria to some drugs revealed statistically significant differences (P<0.05) in the resistance of both to cefoxitin, cotrimoxazole, levofloxacin, cefuroxime, ceftriaxone and ceftazidime, and both had higher rates of resistance to gram-negative bacteria than to gram-positive bacteria. The distribution of bacterial infection strains showed that Staphylococcus epidermidis was the most common strain in the conjunctiva, cornea, aqueous humor or vitreous body and other eye parts. Besides, Fusarium and Pseudomonas aeruginosa were also among the most common strains of conjunctival and corneal infections. CONCLUSION: Gram-positive bacteria are the dominant bacteria in eye infections, followed by gram-negative bacteria and fungi. Considering the resistance of gram-negative bacteria to multiple drugs, monitoring of bacteria should be strengthened in eye bacterial infections for effective prevention and control to reduce complications caused by eye infections.http://ies.ijo.cn/en_publish/2024/4/20240414.pdfeye infectionpathogenic bacteriadrug resistanceantimicrobial sensitivity test |
| spellingShingle | Li Zhang Hai-Zhang You Guo-Hui Wang Wei Xu Jian-Shan Li Qing-Liang Zhao Shu Du Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou International Journal of Ophthalmology eye infection pathogenic bacteria drug resistance antimicrobial sensitivity test |
| title | Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou |
| title_full | Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou |
| title_fullStr | Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou |
| title_full_unstemmed | Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou |
| title_short | Distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in Suzhou |
| title_sort | distribution of pathogenic bacteria and antimicrobial sensitivity of eye infections in suzhou |
| topic | eye infection pathogenic bacteria drug resistance antimicrobial sensitivity test |
| url | http://ies.ijo.cn/en_publish/2024/4/20240414.pdf |
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