6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine
Suzuki coupling reaction of 5-fluoro-6-methylpyridin-2-ylboronic acid (1) with 4-chloro-2-iodo-1-(trifluoromethyl)benzene (2) in the presence of dikis and K2CO3 produce C-C coupled new title compound 6-(5-chloro-2-(trifluoromethyl)phenyl)-3-fluoro-2-methylpyridine (3). The structure of the newly syn...
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-09-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2013/4/M808 |
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| author | Tadimety Harikrishna Mohan Revanasiddappa Nadigar Karikere Ekanna Manojkumar Swamy Sreenivasa |
| author_facet | Tadimety Harikrishna Mohan Revanasiddappa Nadigar Karikere Ekanna Manojkumar Swamy Sreenivasa |
| author_sort | Tadimety Harikrishna |
| collection | DOAJ |
| description | Suzuki coupling reaction of 5-fluoro-6-methylpyridin-2-ylboronic acid (1) with 4-chloro-2-iodo-1-(trifluoromethyl)benzene (2) in the presence of dikis and K2CO3 produce C-C coupled new title compound 6-(5-chloro-2-(trifluoromethyl)phenyl)-3-fluoro-2-methylpyridine (3). The structure of the newly synthesized compound has been confirmed by IR, 1H-NMR, 13C-NMR, LC-MS and CHN analysis. |
| first_indexed | 2024-12-11T20:02:24Z |
| format | Article |
| id | doaj.art-6282c8a0f6104109a88f5068bf9b12a1 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-12-11T20:02:24Z |
| publishDate | 2013-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-6282c8a0f6104109a88f5068bf9b12a12022-12-22T00:52:30ZengMDPI AGMolbank1422-85992013-09-0120134M80810.3390/M8086-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridineTadimety HarikrishnaMohan Revanasiddappa NadigarKarikere Ekanna ManojkumarSwamy SreenivasaSuzuki coupling reaction of 5-fluoro-6-methylpyridin-2-ylboronic acid (1) with 4-chloro-2-iodo-1-(trifluoromethyl)benzene (2) in the presence of dikis and K2CO3 produce C-C coupled new title compound 6-(5-chloro-2-(trifluoromethyl)phenyl)-3-fluoro-2-methylpyridine (3). The structure of the newly synthesized compound has been confirmed by IR, 1H-NMR, 13C-NMR, LC-MS and CHN analysis.http://www.mdpi.com/1422-8599/2013/4/M808Suzuki coupling5-fluoro-6-methylpyridin-2-ylboronic acid4-chloro-2-iodo-1-(trifluoromethyl)benzenebis(triphenylphosphine)palladium(II) dichloride (dikis)1,4-dioxane |
| spellingShingle | Tadimety Harikrishna Mohan Revanasiddappa Nadigar Karikere Ekanna Manojkumar Swamy Sreenivasa 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine Molbank Suzuki coupling 5-fluoro-6-methylpyridin-2-ylboronic acid 4-chloro-2-iodo-1-(trifluoromethyl)benzene bis(triphenylphosphine)palladium(II) dichloride (dikis) 1,4-dioxane |
| title | 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine |
| title_full | 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine |
| title_fullStr | 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine |
| title_full_unstemmed | 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine |
| title_short | 6-[5-Chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine |
| title_sort | 6 5 chloro 2 trifluoromethyl phenyl 3 fluoro 2 methylpyridine |
| topic | Suzuki coupling 5-fluoro-6-methylpyridin-2-ylboronic acid 4-chloro-2-iodo-1-(trifluoromethyl)benzene bis(triphenylphosphine)palladium(II) dichloride (dikis) 1,4-dioxane |
| url | http://www.mdpi.com/1422-8599/2013/4/M808 |
| work_keys_str_mv | AT tadimetyharikrishna 65chloro2trifluoromethylphenyl3fluoro2methylpyridine AT mohanrevanasiddappanadigar 65chloro2trifluoromethylphenyl3fluoro2methylpyridine AT karikereekannamanojkumar 65chloro2trifluoromethylphenyl3fluoro2methylpyridine AT swamysreenivasa 65chloro2trifluoromethylphenyl3fluoro2methylpyridine |