Analysis of Cochrane Systematic Reviews about retinopathy of prematurity
ABSTRACT Background: Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder that affects extremely premature infants and is the leading cause of irreversible blindness in childhood. Objective: This study presents a review of Cochrane systematic reviews about ROP. Methods: We ana...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Oftalmologia
2021-04-01
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| Series: | Revista Brasileira de Oftalmologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000100042&tlng=en |
| _version_ | 1798019949068812288 |
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| author | Vânia Mozetic Matheus Ferreira Santos da Cruz Natasha Ferreira Santos da Cruz Murilo Ubukata Polizelli Nilva Simeren Bueno de Moraes |
| author_facet | Vânia Mozetic Matheus Ferreira Santos da Cruz Natasha Ferreira Santos da Cruz Murilo Ubukata Polizelli Nilva Simeren Bueno de Moraes |
| author_sort | Vânia Mozetic |
| collection | DOAJ |
| description | ABSTRACT Background: Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder that affects extremely premature infants and is the leading cause of irreversible blindness in childhood. Objective: This study presents a review of Cochrane systematic reviews about ROP. Methods: We analyzed and summarized the results of all intervention, prevention and treatment, from Cochrane Systematic Reviews (SR) for ROP designed to the highest standard of rigor to show the current position and propose studies that are missing for decision making. Results: Eight SR were analyzed in this study, four in prophylaxis and four in treatment of ROP. The outcome 'Beneficial effect of oral beta-blockers on progression to stage 3 ROP but not to stage 2 ROP with plus disease or to stage 4 or 5 ROP was the only one that presented moderate evidence quality, all the others outcomes presented evidence quality floating from low to very low. Conclusion: There is a lack of studies showing the quality of evidence in the treatment and prevention of retinopathy of prematurity, particularly in long-term outcomes after treatment in order to assess the impact and quality of life of these patients. |
| first_indexed | 2024-04-11T16:49:57Z |
| format | Article |
| id | doaj.art-6283f17ed07f4e549a75af43cdf1ad01 |
| institution | Directory Open Access Journal |
| issn | 1982-8551 |
| language | English |
| last_indexed | 2024-04-11T16:49:57Z |
| publishDate | 2021-04-01 |
| publisher | Sociedade Brasileira de Oftalmologia |
| record_format | Article |
| series | Revista Brasileira de Oftalmologia |
| spelling | doaj.art-6283f17ed07f4e549a75af43cdf1ad012022-12-22T04:13:28ZengSociedade Brasileira de OftalmologiaRevista Brasileira de Oftalmologia1982-85512021-04-01801424810.5935/0034-7280.20210008Analysis of Cochrane Systematic Reviews about retinopathy of prematurityVânia Mozetichttps://orcid.org/0000-0002-6243-1530Matheus Ferreira Santos da Cruzhttps://orcid.org/0000-0002-2223-4815Natasha Ferreira Santos da Cruzhttps://orcid.org/0000-0002-5209-9204Murilo Ubukata Polizellihttps://orcid.org/0000-0003-2429-216XNilva Simeren Bueno de Moraeshttps://orcid.org/0000-0001-5605-6028ABSTRACT Background: Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder that affects extremely premature infants and is the leading cause of irreversible blindness in childhood. Objective: This study presents a review of Cochrane systematic reviews about ROP. Methods: We analyzed and summarized the results of all intervention, prevention and treatment, from Cochrane Systematic Reviews (SR) for ROP designed to the highest standard of rigor to show the current position and propose studies that are missing for decision making. Results: Eight SR were analyzed in this study, four in prophylaxis and four in treatment of ROP. The outcome 'Beneficial effect of oral beta-blockers on progression to stage 3 ROP but not to stage 2 ROP with plus disease or to stage 4 or 5 ROP was the only one that presented moderate evidence quality, all the others outcomes presented evidence quality floating from low to very low. Conclusion: There is a lack of studies showing the quality of evidence in the treatment and prevention of retinopathy of prematurity, particularly in long-term outcomes after treatment in order to assess the impact and quality of life of these patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000100042&tlng=enRetinopathy of prematurityTherapeuticsProphylaxisEvidence-based practiceEvidence-based medicine |
| spellingShingle | Vânia Mozetic Matheus Ferreira Santos da Cruz Natasha Ferreira Santos da Cruz Murilo Ubukata Polizelli Nilva Simeren Bueno de Moraes Analysis of Cochrane Systematic Reviews about retinopathy of prematurity Revista Brasileira de Oftalmologia Retinopathy of prematurity Therapeutics Prophylaxis Evidence-based practice Evidence-based medicine |
| title | Analysis of Cochrane Systematic Reviews about retinopathy of prematurity |
| title_full | Analysis of Cochrane Systematic Reviews about retinopathy of prematurity |
| title_fullStr | Analysis of Cochrane Systematic Reviews about retinopathy of prematurity |
| title_full_unstemmed | Analysis of Cochrane Systematic Reviews about retinopathy of prematurity |
| title_short | Analysis of Cochrane Systematic Reviews about retinopathy of prematurity |
| title_sort | analysis of cochrane systematic reviews about retinopathy of prematurity |
| topic | Retinopathy of prematurity Therapeutics Prophylaxis Evidence-based practice Evidence-based medicine |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802021000100042&tlng=en |
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