Presep: predicting the propensity of a protein being secreted into the supernatant when expressed in Pichia pastoris.

Pichia pastoris is commonly used for the production of recombinant proteins due to its preferential secretion of recombinant proteins, resulting in lower production costs and increased yields of target proteins. However, not all recombinant proteins can be successfully secreted in P. pastoris. A com...

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Bibliographic Details
Main Authors: Jian Tian, Yuhong Zhang, Bo Liu, Dongyang Zuo, Tao Jiang, Jun Guo, Wei Zhang, Ningfeng Wu, Yunliu Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3836778?pdf=render