Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division
Proteins FtsZ, ZipA, and either PBP1A or PBP1B are required for the synthesis of preseptal peptidoglycan at the future cell division site in E. coli. Here, Pazos et al. provide evidence that ZipA and FtsA-FtsN connect the cytosolic FtsZ ring with the membrane-anchored PBPs.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07559-2 |
| _version_ | 1818841314974760960 |
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| author | Manuel Pazos Katharina Peters Mercedes Casanova Pilar Palacios Michael VanNieuwenhze Eefjan Breukink Miguel Vicente Waldemar Vollmer |
| author_facet | Manuel Pazos Katharina Peters Mercedes Casanova Pilar Palacios Michael VanNieuwenhze Eefjan Breukink Miguel Vicente Waldemar Vollmer |
| author_sort | Manuel Pazos |
| collection | DOAJ |
| description | Proteins FtsZ, ZipA, and either PBP1A or PBP1B are required for the synthesis of preseptal peptidoglycan at the future cell division site in E. coli. Here, Pazos et al. provide evidence that ZipA and FtsA-FtsN connect the cytosolic FtsZ ring with the membrane-anchored PBPs. |
| first_indexed | 2024-12-19T04:24:07Z |
| format | Article |
| id | doaj.art-6285ee4d3fe44f16961d2d40a141e1be |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T04:24:07Z |
| publishDate | 2018-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-6285ee4d3fe44f16961d2d40a141e1be2022-12-21T20:36:04ZengNature PortfolioNature Communications2041-17232018-11-019111210.1038/s41467-018-07559-2Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell divisionManuel Pazos0Katharina Peters1Mercedes Casanova2Pilar Palacios3Michael VanNieuwenhze4Eefjan Breukink5Miguel Vicente6Waldemar Vollmer7Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle UniversityCentre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle UniversityCentro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3Molecular and Cellular Biochemistry Department, Biology Department, Indiana UniversityMembrane Biochemistry and Biophysics, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht UniversityCentro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), Darwin 3Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle UniversityProteins FtsZ, ZipA, and either PBP1A or PBP1B are required for the synthesis of preseptal peptidoglycan at the future cell division site in E. coli. Here, Pazos et al. provide evidence that ZipA and FtsA-FtsN connect the cytosolic FtsZ ring with the membrane-anchored PBPs.https://doi.org/10.1038/s41467-018-07559-2 |
| spellingShingle | Manuel Pazos Katharina Peters Mercedes Casanova Pilar Palacios Michael VanNieuwenhze Eefjan Breukink Miguel Vicente Waldemar Vollmer Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division Nature Communications |
| title | Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| title_full | Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| title_fullStr | Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| title_full_unstemmed | Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| title_short | Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| title_sort | z ring membrane anchors associate with cell wall synthases to initiate bacterial cell division |
| url | https://doi.org/10.1038/s41467-018-07559-2 |
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