Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent

The effects of the chemical effluent from Soap and Detergent Industry on some rat liver enzymes were investigated. Chemical analyses of both the effluent and tap water which served as the control were carried out before various concentrations of the effluent (5%v/v, 25%v/v, 50%v/v and 100%v/v) were...

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Main Authors: OB Oloyede, TO Sunmonu
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2010-06-01
Series:Journal of Applied Sciences and Environmental Management
Online Access:https://www.ajol.info/index.php/jasem/article/view/55510
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author OB Oloyede
TO Sunmonu
author_facet OB Oloyede
TO Sunmonu
author_sort OB Oloyede
collection DOAJ
description The effects of the chemical effluent from Soap and Detergent Industry on some rat liver enzymes were investigated. Chemical analyses of both the effluent and tap water which served as the control were carried out before various concentrations of the effluent (5%v/v, 25%v/v, 50%v/v and 100%v/v) were made. The effluent as collected from source represents 100%v/v. Four groups of five (5) rats each were placed on the four concentrations of the effluent prepared as the only source of water for thirty (30) days. The rats in the fifth group which served as the control were placed on tap water for the same period of time. All the rats were maintained on commercial rat chow for the duration of the experiment. At the end of the experiment, the animals were sacrificed and blood samples were collected. The effect of the chemical effluent on rat liver was monitored by conducting standard enzyme assays for alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST) and lactate dehydrogenase (LDH) in the liver and serum of experimental animals. Relative to the control, significant (p
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spelling doaj.art-62861c9ffc704c2d82536e85df09d7022024-04-02T19:57:05ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992010-06-0112310.4314/jasem.v12i3.55510Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical EffluentOB OloyedeTO SunmonuThe effects of the chemical effluent from Soap and Detergent Industry on some rat liver enzymes were investigated. Chemical analyses of both the effluent and tap water which served as the control were carried out before various concentrations of the effluent (5%v/v, 25%v/v, 50%v/v and 100%v/v) were made. The effluent as collected from source represents 100%v/v. Four groups of five (5) rats each were placed on the four concentrations of the effluent prepared as the only source of water for thirty (30) days. The rats in the fifth group which served as the control were placed on tap water for the same period of time. All the rats were maintained on commercial rat chow for the duration of the experiment. At the end of the experiment, the animals were sacrificed and blood samples were collected. The effect of the chemical effluent on rat liver was monitored by conducting standard enzyme assays for alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST) and lactate dehydrogenase (LDH) in the liver and serum of experimental animals. Relative to the control, significant (phttps://www.ajol.info/index.php/jasem/article/view/55510
spellingShingle OB Oloyede
TO Sunmonu
Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
Journal of Applied Sciences and Environmental Management
title Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
title_full Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
title_fullStr Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
title_full_unstemmed Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
title_short Decrease in Activities of Selected Rat Liver Enzymes following Consumption of Chemical Effluent
title_sort decrease in activities of selected rat liver enzymes following consumption of chemical effluent
url https://www.ajol.info/index.php/jasem/article/view/55510
work_keys_str_mv AT oboloyede decreaseinactivitiesofselectedratliverenzymesfollowingconsumptionofchemicaleffluent
AT tosunmonu decreaseinactivitiesofselectedratliverenzymesfollowingconsumptionofchemicaleffluent