Molecular alterations in signal pathways of melanoma and new personalized treatment strategies: Targeting of Notch

Molecular alterations in signal pathways of melanoma and new personalized treatment strategies: Targeting of Notch

Despite modern achievements in therapy of malignant melanomas new treatment strategies are welcomed in clinics for survival of patients. Now it is supposed that personalized molecular therapies for each patient are needed concerning a specificity of molecular alterations in patient's tumors. In...

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Bibliographic Details
Main Authors: Julija Mozūraitienė, Kristina Bielskienė, Vydmantas Atkočius, Danutė Labeikytė
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Medicina
Subjects:
Notch pathway
p53 pathway
MDM2 E3 ubiquitin ligase
MDM4 E3 ubiquitin ligase
Melanoma
Online Access:http://www.sciencedirect.com/science/article/pii/S1010660X15000439

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