THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) a...
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Format: | Article |
Language: | English |
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Eco-vector
2017-09-01
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Series: | Клиническая практика |
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Online Access: | https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469 |
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author | T V Stavenchuk E D Kosmachova I A Shelestova A A Slavinsky E A Terman A A Verevkin L A Medvedeva K O Barbuhatty Z G Tatarintseva V A Porchanov |
author_facet | T V Stavenchuk E D Kosmachova I A Shelestova A A Slavinsky E A Terman A A Verevkin L A Medvedeva K O Barbuhatty Z G Tatarintseva V A Porchanov |
author_sort | T V Stavenchuk |
collection | DOAJ |
description | The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%). |
first_indexed | 2024-03-12T07:09:12Z |
format | Article |
id | doaj.art-628a14ddfa3b479f83a950a8b73d69e9 |
institution | Directory Open Access Journal |
issn | 2220-3095 2618-8627 |
language | English |
last_indexed | 2024-03-12T07:09:12Z |
publishDate | 2017-09-01 |
publisher | Eco-vector |
record_format | Article |
series | Клиническая практика |
spelling | doaj.art-628a14ddfa3b479f83a950a8b73d69e92023-09-02T23:15:04ZengEco-vectorКлиническая практика2220-30952618-86272017-09-0183283310.17816/clinpract8328-337493THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTST V StavenchukE D KosmachovaI A ShelestovaA A SlavinskyE A TermanA A VerevkinL A MedvedevaK O BarbuhattyZ G TatarintsevaV A PorchanovThe following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469computerised morphometric studyendomyocardial biopsyheart transplant rejection |
spellingShingle | T V Stavenchuk E D Kosmachova I A Shelestova A A Slavinsky E A Terman A A Verevkin L A Medvedeva K O Barbuhatty Z G Tatarintseva V A Porchanov THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS Клиническая практика computerised morphometric study endomyocardial biopsy heart transplant rejection |
title | THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS |
title_full | THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS |
title_fullStr | THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS |
title_full_unstemmed | THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS |
title_short | THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS |
title_sort | problem of heart transplant rejection and ways of optimizing the assessment of endomyocardial biopsy results |
topic | computerised morphometric study endomyocardial biopsy heart transplant rejection |
url | https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469 |
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