THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS

The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) a...

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Main Authors: T V Stavenchuk, E D Kosmachova, I A Shelestova, A A Slavinsky, E A Terman, A A Verevkin, L A Medvedeva, K O Barbuhatty, Z G Tatarintseva, V A Porchanov
Format: Article
Language:English
Published: Eco-vector 2017-09-01
Series:Клиническая практика
Subjects:
Online Access:https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469
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author T V Stavenchuk
E D Kosmachova
I A Shelestova
A A Slavinsky
E A Terman
A A Verevkin
L A Medvedeva
K O Barbuhatty
Z G Tatarintseva
V A Porchanov
author_facet T V Stavenchuk
E D Kosmachova
I A Shelestova
A A Slavinsky
E A Terman
A A Verevkin
L A Medvedeva
K O Barbuhatty
Z G Tatarintseva
V A Porchanov
author_sort T V Stavenchuk
collection DOAJ
description The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).
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spelling doaj.art-628a14ddfa3b479f83a950a8b73d69e92023-09-02T23:15:04ZengEco-vectorКлиническая практика2220-30952618-86272017-09-0183283310.17816/clinpract8328-337493THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTST V StavenchukE D KosmachovaI A ShelestovaA A SlavinskyE A TermanA A VerevkinL A MedvedevaK O BarbuhattyZ G TatarintsevaV A PorchanovThe following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469computerised morphometric studyendomyocardial biopsyheart transplant rejection
spellingShingle T V Stavenchuk
E D Kosmachova
I A Shelestova
A A Slavinsky
E A Terman
A A Verevkin
L A Medvedeva
K O Barbuhatty
Z G Tatarintseva
V A Porchanov
THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
Клиническая практика
computerised morphometric study
endomyocardial biopsy
heart transplant rejection
title THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
title_full THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
title_fullStr THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
title_full_unstemmed THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
title_short THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
title_sort problem of heart transplant rejection and ways of optimizing the assessment of endomyocardial biopsy results
topic computerised morphometric study
endomyocardial biopsy
heart transplant rejection
url https://journals.eco-vector.com/clinpractice/article/viewFile/8046/6469
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