Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer
Alpha-fetoprotein producing gastric cancer (AFPGC) is a special type of gastric cancer. AFPGC is considered to be the most highly invasive tumor with a high degree of malignancy and prone to metastasis. As a consequence, it usually causes unsatisfied treatment effect and the prognosis is poor. At pr...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Magazine House of Cancer Research on Prevention and Treatment
2022-07-01
|
| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1273 |
| _version_ | 1828373961901080576 |
|---|---|
| author | LU Shunli YU Jianping CHEN Weikai LI Andong HE Qingyuan CHEN Chao HAN Xiaopeng |
| author_facet | LU Shunli YU Jianping CHEN Weikai LI Andong HE Qingyuan CHEN Chao HAN Xiaopeng |
| author_sort | LU Shunli |
| collection | DOAJ |
| description | Alpha-fetoprotein producing gastric cancer (AFPGC) is a special type of gastric cancer. AFPGC is considered to be the most highly invasive tumor with a high degree of malignancy and prone to metastasis. As a consequence, it usually causes unsatisfied treatment effect and the prognosis is poor. At present, treatment methods and monitoring indicators have limited effect on AFPGC. VEGF, HER2, AFP, GPC3 and SALL4 are cogently associated with tumor genesis and development. If we can reasonably guide the treatment and prognosis of AFPGC patients, it will greatly improve the situation of patients and improve the survival of patients. This article reviews the research progress of the genes related to the treatment and prognosis of AFPGC. |
| first_indexed | 2024-04-14T07:27:25Z |
| format | Article |
| id | doaj.art-628bf3ae15ae4650a066acc1950def79 |
| institution | Directory Open Access Journal |
| issn | 1000-8578 |
| language | zho |
| last_indexed | 2024-04-14T07:27:25Z |
| publishDate | 2022-07-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj.art-628bf3ae15ae4650a066acc1950def792022-12-22T02:05:59ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782022-07-0149773874410.3971/j.issn.1000-8578.2022.21.12738578.2022.21.1273Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric CancerLU Shunli0YU Jianping1CHEN Weikai2LI Andong3HE Qingyuan4CHEN Chao5HAN Xiaopeng6The First Clinical Medicine College of Gansu University of Chinese Medicine, Lanzhou 730000, ChinaDepartment of General Surgery, Gansu Central Hospital, Lanzhou 730070, ChinaDepartment of General Surgery, Gansu Central Hospital, Lanzhou 730070, ChinaDepartment of General Surgery, 940 Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, ChinaDepartment of General Surgery, 940 Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, ChinaDepartment of General Surgery, 940 Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, ChinaDepartment of General Surgery, 940 Hospital of PLA Joint Logistics Support Force, Lanzhou 730050, ChinaAlpha-fetoprotein producing gastric cancer (AFPGC) is a special type of gastric cancer. AFPGC is considered to be the most highly invasive tumor with a high degree of malignancy and prone to metastasis. As a consequence, it usually causes unsatisfied treatment effect and the prognosis is poor. At present, treatment methods and monitoring indicators have limited effect on AFPGC. VEGF, HER2, AFP, GPC3 and SALL4 are cogently associated with tumor genesis and development. If we can reasonably guide the treatment and prognosis of AFPGC patients, it will greatly improve the situation of patients and improve the survival of patients. This article reviews the research progress of the genes related to the treatment and prognosis of AFPGC.http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1273alpha-fetoprotein producing gastric cancergenesmolecular mechanismstherapyprognoses |
| spellingShingle | LU Shunli YU Jianping CHEN Weikai LI Andong HE Qingyuan CHEN Chao HAN Xiaopeng Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer Zhongliu Fangzhi Yanjiu alpha-fetoprotein producing gastric cancer genes molecular mechanisms therapy prognoses |
| title | Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer |
| title_full | Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer |
| title_fullStr | Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer |
| title_full_unstemmed | Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer |
| title_short | Research Progress of Genes Related to Treatment and Prognosis of Alpha-fetoprotein Producing Gastric Cancer |
| title_sort | research progress of genes related to treatment and prognosis of alpha fetoprotein producing gastric cancer |
| topic | alpha-fetoprotein producing gastric cancer genes molecular mechanisms therapy prognoses |
| url | http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.21.1273 |
| work_keys_str_mv | AT lushunli researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT yujianping researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT chenweikai researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT liandong researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT heqingyuan researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT chenchao researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer AT hanxiaopeng researchprogressofgenesrelatedtotreatmentandprognosisofalphafetoproteinproducinggastriccancer |