Role of endothelial dysfunction in pathogenesis of atherosclerosis
Accoding to modern views, endothelial dysfunction is considered to be the key link in pathogenesis of atherosclerosis, manifesting in imbalance between endothelial vasoactive substances – vasodilators and vasoconstrictors. Is demonstrated, that practically all risk factors of atherosclerosis realise...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics
2011-06-01
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| Series: | Атеросклероз |
| Subjects: | |
| Online Access: | https://ateroskleroz.elpub.ru/jour/article/view/602/539 |
| _version_ | 1797963010063466496 |
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| author | Yu. P. Nikitin G. I. Simonova M. A. Khoreva R. I. Vorobiov E. N. Vorobiova G. I. Shumaher I. V. Osipova I. B. Kyperman |
| author_facet | Yu. P. Nikitin G. I. Simonova M. A. Khoreva R. I. Vorobiov E. N. Vorobiova G. I. Shumaher I. V. Osipova I. B. Kyperman |
| author_sort | Yu. P. Nikitin |
| collection | DOAJ |
| description | Accoding to modern views, endothelial dysfunction is considered to be the key link in pathogenesis of atherosclerosis, manifesting in imbalance between endothelial vasoactive substances – vasodilators and vasoconstrictors. Is demonstrated, that practically all risk factors of atherosclerosis realises the unfavorable effect through endothelial dysfunction. In this connection, is actual to asses the indexes of endothelial function in men with risk factors of atherosclerosis as the markers of early atherosclerotic changes of vessels. The assigning of pathogenetic therapy at this stage, and also for faces with the demonstrated atherosclerosis will allow considerably improve the prognosis of patients. |
| first_indexed | 2024-04-11T01:21:39Z |
| format | Article |
| id | doaj.art-628d435dde1e4ba78d52bd961bf711a7 |
| institution | Directory Open Access Journal |
| issn | 2078-256X |
| language | Russian |
| last_indexed | 2024-04-11T01:21:39Z |
| publishDate | 2011-06-01 |
| publisher | Siberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and Genetics |
| record_format | Article |
| series | Атеросклероз |
| spelling | doaj.art-628d435dde1e4ba78d52bd961bf711a72023-01-03T11:17:20ZrusSiberian Branch of Russian Academy of Sciences, Research Institute of Internal and Preventive Medicine, branch of the Institute of Cytology and GeneticsАтеросклероз2078-256X2011-06-01716069Role of endothelial dysfunction in pathogenesis of atherosclerosisYu. P. Nikitin0 G. I. Simonova1M. A. Khoreva2R. I. Vorobiov3 E. N. Vorobiova4G. I. Shumaher5I. V. Osipova6I. B. Kyperman7RAMS Russian Federation SB RAMS Institution of the Russian Academy of Medical Sciences Research Institute of TherapyRAMS Russian Federation SB RAMS Institution of the Russian Academy of Medical Sciences Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyRAMS; Roszdrav Russian Federation SB RAMS Altai State Medical University Research Institute of TherapyAccoding to modern views, endothelial dysfunction is considered to be the key link in pathogenesis of atherosclerosis, manifesting in imbalance between endothelial vasoactive substances – vasodilators and vasoconstrictors. Is demonstrated, that practically all risk factors of atherosclerosis realises the unfavorable effect through endothelial dysfunction. In this connection, is actual to asses the indexes of endothelial function in men with risk factors of atherosclerosis as the markers of early atherosclerotic changes of vessels. The assigning of pathogenetic therapy at this stage, and also for faces with the demonstrated atherosclerosis will allow considerably improve the prognosis of patients.https://ateroskleroz.elpub.ru/jour/article/view/602/539atherosclerosisendothelial dysfunctionrisk factorsnitric oxide |
| spellingShingle | Yu. P. Nikitin G. I. Simonova M. A. Khoreva R. I. Vorobiov E. N. Vorobiova G. I. Shumaher I. V. Osipova I. B. Kyperman Role of endothelial dysfunction in pathogenesis of atherosclerosis Атеросклероз atherosclerosis endothelial dysfunction risk factors nitric oxide |
| title | Role of endothelial dysfunction in pathogenesis of atherosclerosis |
| title_full | Role of endothelial dysfunction in pathogenesis of atherosclerosis |
| title_fullStr | Role of endothelial dysfunction in pathogenesis of atherosclerosis |
| title_full_unstemmed | Role of endothelial dysfunction in pathogenesis of atherosclerosis |
| title_short | Role of endothelial dysfunction in pathogenesis of atherosclerosis |
| title_sort | role of endothelial dysfunction in pathogenesis of atherosclerosis |
| topic | atherosclerosis endothelial dysfunction risk factors nitric oxide |
| url | https://ateroskleroz.elpub.ru/jour/article/view/602/539 |
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