A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial
Plain English Summary Patients hospitalised with anorexia nervosa require nutrition support as part of their treatment, whilst refeeding complications are prevented. Of particular concern, is the reintroduction of carbohydrate to malnourished patients, which has been proposed to cause a surge in ins...
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-12-01
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| Series: | Journal of Eating Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40337-021-00513-6 |
| _version_ | 1828046470343819264 |
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| author | Elizabeth Kumiko Parker Victoria Flood Mark Halaki Christine Wearne Gail Anderson Linette Gomes Simon Clarke Frances Wilson Janice Russell Elizabeth Frig Michael Kohn |
| author_facet | Elizabeth Kumiko Parker Victoria Flood Mark Halaki Christine Wearne Gail Anderson Linette Gomes Simon Clarke Frances Wilson Janice Russell Elizabeth Frig Michael Kohn |
| author_sort | Elizabeth Kumiko Parker |
| collection | DOAJ |
| description | Plain English Summary Patients hospitalised with anorexia nervosa require nutrition support as part of their treatment, whilst refeeding complications are prevented. Of particular concern, is the reintroduction of carbohydrate to malnourished patients, which has been proposed to cause a surge in insulin levels and disturbance in electrolytes, particularly a decrease in blood phosphate levels. This double-blinded randomised controlled trial measured the occurrence of low phosphate blood levels and other refeeding complications, in adolescent and young adult patients hospitalised with anorexia nervosa. These patients were provided either a lower carbohydrate/high fat feed (28% carbohydrate, 56% fat) or a standard enteral feed (54% carbohydrate, 29% fat). Fewer patients in the lower carbohydrate/high fat feed group (5/14) than standard feed group (9/10) developed a low phosphate level. There was no significant difference in weight gain, number of days to reach medical stability, occurrence of hypoglycaemia, or hospital length of stay. |
| first_indexed | 2024-04-10T18:26:37Z |
| format | Article |
| id | doaj.art-628e042cd21944059b63443b7cc5142e |
| institution | Directory Open Access Journal |
| issn | 2050-2974 |
| language | English |
| last_indexed | 2024-04-10T18:26:37Z |
| publishDate | 2021-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Eating Disorders |
| spelling | doaj.art-628e042cd21944059b63443b7cc5142e2023-02-02T05:31:17ZengBMCJournal of Eating Disorders2050-29742021-12-019111210.1186/s40337-021-00513-6A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trialElizabeth Kumiko Parker0Victoria Flood1Mark Halaki2Christine Wearne3Gail Anderson4Linette Gomes5Simon Clarke6Frances Wilson7Janice Russell8Elizabeth Frig9Michael Kohn10Department of Dietetics and Nutrition, Westmead HospitalSydney School of Health Sciences, Faculty of Medicine and Health, The University of SydneySydney School of Health Sciences, Faculty of Medicine and Health, The University of SydneyDepartment of Medical Psychology, Westmead HospitalDepartment of Adolescent and Young Adult Medicine, Westmead HospitalDepartment of Adolescent and Young Adult Medicine, Westmead HospitalDepartment of Adolescent and Young Adult Medicine, Westmead HospitalDepartment of Psychiatry, Westmead HospitalSydney School of Medicine, Faculty of Medicine and Health, The University of SydneyDepartment of Nutrition and Dietetics, Royal Prince Alfred HospitalDepartment of Adolescent and Young Adult Medicine, Westmead HospitalPlain English Summary Patients hospitalised with anorexia nervosa require nutrition support as part of their treatment, whilst refeeding complications are prevented. Of particular concern, is the reintroduction of carbohydrate to malnourished patients, which has been proposed to cause a surge in insulin levels and disturbance in electrolytes, particularly a decrease in blood phosphate levels. This double-blinded randomised controlled trial measured the occurrence of low phosphate blood levels and other refeeding complications, in adolescent and young adult patients hospitalised with anorexia nervosa. These patients were provided either a lower carbohydrate/high fat feed (28% carbohydrate, 56% fat) or a standard enteral feed (54% carbohydrate, 29% fat). Fewer patients in the lower carbohydrate/high fat feed group (5/14) than standard feed group (9/10) developed a low phosphate level. There was no significant difference in weight gain, number of days to reach medical stability, occurrence of hypoglycaemia, or hospital length of stay.https://doi.org/10.1186/s40337-021-00513-6Anorexia nervosaEnteral nutritionRefeeding syndromeHypophosphatemiaCarbohydrate |
| spellingShingle | Elizabeth Kumiko Parker Victoria Flood Mark Halaki Christine Wearne Gail Anderson Linette Gomes Simon Clarke Frances Wilson Janice Russell Elizabeth Frig Michael Kohn A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial Journal of Eating Disorders Anorexia nervosa Enteral nutrition Refeeding syndrome Hypophosphatemia Carbohydrate |
| title | A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial |
| title_full | A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial |
| title_fullStr | A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial |
| title_full_unstemmed | A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial |
| title_short | A standard enteral formula versus an iso-caloric lower carbohydrate/high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa: a randomised controlled trial |
| title_sort | standard enteral formula versus an iso caloric lower carbohydrate high fat enteral formula in the hospital management of adolescent and young adults admitted with anorexia nervosa a randomised controlled trial |
| topic | Anorexia nervosa Enteral nutrition Refeeding syndrome Hypophosphatemia Carbohydrate |
| url | https://doi.org/10.1186/s40337-021-00513-6 |
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