Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment
Composites of tetracycline (Tc)-imprinted polymethacrylates and quantum dots have been coated on chemically pretreated polyimide substrates (PIs) as fluorescent sensors. In this study, PIs were pretreated by capacitively coupled plasma (CCP) before coating the same composites on them. For the first...
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MDPI AG
2020-05-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/9/2723 |
| _version_ | 1797568298164944896 |
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| author | Ching-Bin Ke Jian-Lian Chen |
| author_facet | Ching-Bin Ke Jian-Lian Chen |
| author_sort | Ching-Bin Ke |
| collection | DOAJ |
| description | Composites of tetracycline (Tc)-imprinted polymethacrylates and quantum dots have been coated on chemically pretreated polyimide substrates (PIs) as fluorescent sensors. In this study, PIs were pretreated by capacitively coupled plasma (CCP) before coating the same composites on them. For the first time, to fabricate sensors by plasma modification of PIs, the CCP conditions, including plasma gas, flow rate, radio frequency generation power, and duration time, the fabrication details, including coating, baking, and stripping steps, and the sample loading process were optimized to perform a linear decrease in fluorescent intensity with Tc concentrations in the range of 5.0–3000 μM (R<sup>2</sup> = 0.9995) with a limit of detection of 0.2 μM (S/N = 3, relative standard deviation (RSD) = 2.2%). The selectivity of the stripped PIs was evaluated by the imprinting factors (IFs) for Tc (IF = 7.2), other Tc analogues (IF = 3.4–5.3), and steroids (IF ≈ 1) and by the recoveries of 5.0 μM Tc from bovine serum albumin at 300 μg∙mL<sup>−1</sup> (98%, RSD = 3.2%), fetal bovine serum at 1.5 ppt (98%, RSD = 2.8%), and liquid milk (94.5%, RSD = 5.3%). The superiority of the present plasma-treated-based sensor over the previous chemically-treated one in fabrication efficiency and detection effectiveness was clear. |
| first_indexed | 2024-03-10T19:55:29Z |
| format | Article |
| id | doaj.art-628eb2410e75468c96a7906914eddd07 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T19:55:29Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
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| series | Sensors |
| spelling | doaj.art-628eb2410e75468c96a7906914eddd072023-11-20T00:00:14ZengMDPI AGSensors1424-82202020-05-01209272310.3390/s20092723Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical PretreatmentChing-Bin Ke0Jian-Lian Chen1Department of Beauty and Health Care, Min-Hwei Junior College of Health Care Management, No.1116, Sec 2, Zhongshan E. Rd., Tainan 73658, TaiwanSchool of Pharmacy, China Medical University, No. 91 Hsueh-Shih Road, Taichung 40402, TaiwanComposites of tetracycline (Tc)-imprinted polymethacrylates and quantum dots have been coated on chemically pretreated polyimide substrates (PIs) as fluorescent sensors. In this study, PIs were pretreated by capacitively coupled plasma (CCP) before coating the same composites on them. For the first time, to fabricate sensors by plasma modification of PIs, the CCP conditions, including plasma gas, flow rate, radio frequency generation power, and duration time, the fabrication details, including coating, baking, and stripping steps, and the sample loading process were optimized to perform a linear decrease in fluorescent intensity with Tc concentrations in the range of 5.0–3000 μM (R<sup>2</sup> = 0.9995) with a limit of detection of 0.2 μM (S/N = 3, relative standard deviation (RSD) = 2.2%). The selectivity of the stripped PIs was evaluated by the imprinting factors (IFs) for Tc (IF = 7.2), other Tc analogues (IF = 3.4–5.3), and steroids (IF ≈ 1) and by the recoveries of 5.0 μM Tc from bovine serum albumin at 300 μg∙mL<sup>−1</sup> (98%, RSD = 3.2%), fetal bovine serum at 1.5 ppt (98%, RSD = 2.8%), and liquid milk (94.5%, RSD = 5.3%). The superiority of the present plasma-treated-based sensor over the previous chemically-treated one in fabrication efficiency and detection effectiveness was clear.https://www.mdpi.com/1424-8220/20/9/2723fluorescenceimprinted polymerplasmapolyimidequantum dottetracycline |
| spellingShingle | Ching-Bin Ke Jian-Lian Chen Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment Sensors fluorescence imprinted polymer plasma polyimide quantum dot tetracycline |
| title | Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment |
| title_full | Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment |
| title_fullStr | Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment |
| title_full_unstemmed | Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment |
| title_short | Effective and Efficient Pretreatment of Polyimide Substrates by Capacitively Coupled Plasma for Coating the Composites of Tetracycline-Imprinted Polymers and Quantum Dots: Comparison with Chemical Pretreatment |
| title_sort | effective and efficient pretreatment of polyimide substrates by capacitively coupled plasma for coating the composites of tetracycline imprinted polymers and quantum dots comparison with chemical pretreatment |
| topic | fluorescence imprinted polymer plasma polyimide quantum dot tetracycline |
| url | https://www.mdpi.com/1424-8220/20/9/2723 |
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