Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung

Distinct genomic features between osteosarcomas firstly metastasing to bone and to lung

Background: Osteosarcoma initially metastasing to bone only shows distinct biological features compared to osteosarcoma that firstly metastasizes to the lung, which suggests us underlying different genomic pathogenetic mechanism. Methods: We analyzed whole-exome sequencing (WES) data for 38 osteosar...

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Bibliographic Details
Main Authors: Lu Xie, Zhenyu Cai, Hezhe Lu, Fanfei Meng, Xin Zhang, Kun Luo, Xiaoxing Su, Yan Lei, Jiuhui Xu, Jingbing Lou, Han Wang, Zhiye Du, Yunfan Wang, Yuan Li, Tingting Ren, Jie Xu, Xin Sun, Xiaodong Tang, Wei Guo
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Osteosarcoma
Metastases
Single-nucleotide variation (SNV)
Structural variation (SV)
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023027342

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http://www.sciencedirect.com/science/article/pii/S2405844023027342

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