Activity of natural and synthetic naphthoquinones against Toxoplasma gondii, in vitro and in murine models of infection

Activity of natural and synthetic naphthoquinones against Toxoplasma gondii, in vitro and in murine models of infection

The effect of 14 natural and synthetic naphthoquinones in the replication of Toxoplasma gondii was evaluated. In vitro studies were accomplished in cultures of 2C4 fibroblasts infected with RH- strain. Enzyme-linked immunosorbent assay was used to quantify parasite growth. For the studies in vivo, m...

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Bibliographic Details
Main Authors: Ferreira R.A., Oliveira A.B., Gualberto S.A., Vitor R.W.A.
Format: Article
Language:English
Published: EDP Sciences 2002-09-01
Series:Parasite
Subjects:
naphthoquinones
Toxoplasma gondii
strain
in vitro
murine models
Online Access:http://dx.doi.org/10.1051/parasite/2002093261

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