Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo.

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo.

Advances in cancer therapy have increased the rate of survival of young cancer patients; however, female lymphoma patients frequently face a temporary or permanent loss of fertility when treated with traditional cytotoxic agents. The potential loss of fertility is an important concern that can influ...

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Bibliographic Details
Main Authors: Richard W Ahn, Susan L Barrett, Meera R Raja, Jennifer K Jozefik, Lidia Spaho, Haimei Chen, Marcel B Bally, Andrew P Mazar, Michael J Avram, Jane N Winter, Leo I Gordon, Lonnie D Shea, Thomas V O'Halloran, Teresa K Woodruff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3603968?pdf=render

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