Aberrant METTL14 gene expression contributes to malignant transformation of benzene-exposed myeloid cells

Aberrant METTL14 gene expression contributes to malignant transformation of benzene-exposed myeloid cells

Benzene is a known contributor to human leukaemia through its toxic effects on bone marrow cells, and epigenetic modification is believed to be a potential mechanism underlying benzene pathogenesis. However, the specific roles of N6-methyladenosine (m6A), a newly discovered RNA post-transcriptional...

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Bibliographic Details
Main Authors: Chao Wu, Xin Yu, Xiaoling Li, Ran An, Shengnan Li, Xinyue Liu, Xiangting Hu, Shufei Li, Qinghong Zhou, Limei Li, Hai Yu, Miao Zhao, Antao Chang
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Benzene
N6-methyladenosine (m6A) modification
METTL14
Marrow cells
Malignant transformation
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324003786

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