Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report
We present the case of a 39-year-old woman, G1P0, who had conceived twins via in-vitro fertilization, who presented at 27 weeks of gestation with nasal congestion and dry cough for 7 days. On presentation, her physical examination was benign, except for sinus tachycardia, and she was oxygenating ade...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-07-01
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| Series: | Case Reports in Women's Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911220300503 |
| _version_ | 1818940560075915264 |
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| author | Harsh Mehta Sasa Ivanovic Amanda Cronin Lindsey VanBrunt Nirav Mistry Richard Miller Paul Yodice Fariborz Rezai |
| author_facet | Harsh Mehta Sasa Ivanovic Amanda Cronin Lindsey VanBrunt Nirav Mistry Richard Miller Paul Yodice Fariborz Rezai |
| author_sort | Harsh Mehta |
| collection | DOAJ |
| description | We present the case of a 39-year-old woman, G1P0, who had conceived twins via in-vitro fertilization, who presented at 27 weeks of gestation with nasal congestion and dry cough for 7 days. On presentation, her physical examination was benign, except for sinus tachycardia, and she was oxygenating adequately on room air. Laboratory studies were unremarkable, except a PCR test positive for SARS-COV2, and a CT scan of her chest showed bilateral multi-focal ground-glass opacities. A fetal non-stress test was reassuring. She was treated with intravenous fluids, ceftriaxone, azithromycin, and hydroxychloroquine. During her hospital stay, she developed progressively worsening respiratory failure, initially requiring non-invasive ventilation, and subsequently progressed to acute respiratory distress syndrome requiring mechanical ventilation. She then suffered from sudden hypoxemia and hemodynamic collapse, on maximal ventilatory support, prompting an emergency cesarean section at bedside. This led to rapid stabilization of hemodynamic parameters, and of her overall respiratory status. Both the twins were born prematurely, and one of them tested positive for SARS-COV2. |
| first_indexed | 2024-12-20T06:41:35Z |
| format | Article |
| id | doaj.art-6295e22a98694f828e4656d35698cbe4 |
| institution | Directory Open Access Journal |
| issn | 2214-9112 |
| language | English |
| last_indexed | 2024-12-20T06:41:35Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj.art-6295e22a98694f828e4656d35698cbe42022-12-21T19:49:50ZengElsevierCase Reports in Women's Health2214-91122020-07-0127e00220Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case reportHarsh Mehta0Sasa Ivanovic1Amanda Cronin2Lindsey VanBrunt3Nirav Mistry4Richard Miller5Paul Yodice6Fariborz Rezai7Saint Barnabas Medical Center, Department of Medicine, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Medicine, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Obstetrics and Gynecology, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Obstetrics and Gynecology, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Medicine, Livingston, NJ 07039, USA; Saint Barnabas Medical Center, Division of Critical Care, Department of Medicine, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Obstetrics and Gynecology, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Medicine, Livingston, NJ 07039, USA; Saint Barnabas Medical Center, Division of Critical Care, Department of Medicine, Livingston, NJ 07039, USASaint Barnabas Medical Center, Department of Medicine, Livingston, NJ 07039, USA; Saint Barnabas Medical Center, Division of Critical Care, Department of Medicine, Livingston, NJ 07039, USA; Corresponding author at: 94 Old Short Hills Road, Livingston, NJ 07039, USA.We present the case of a 39-year-old woman, G1P0, who had conceived twins via in-vitro fertilization, who presented at 27 weeks of gestation with nasal congestion and dry cough for 7 days. On presentation, her physical examination was benign, except for sinus tachycardia, and she was oxygenating adequately on room air. Laboratory studies were unremarkable, except a PCR test positive for SARS-COV2, and a CT scan of her chest showed bilateral multi-focal ground-glass opacities. A fetal non-stress test was reassuring. She was treated with intravenous fluids, ceftriaxone, azithromycin, and hydroxychloroquine. During her hospital stay, she developed progressively worsening respiratory failure, initially requiring non-invasive ventilation, and subsequently progressed to acute respiratory distress syndrome requiring mechanical ventilation. She then suffered from sudden hypoxemia and hemodynamic collapse, on maximal ventilatory support, prompting an emergency cesarean section at bedside. This led to rapid stabilization of hemodynamic parameters, and of her overall respiratory status. Both the twins were born prematurely, and one of them tested positive for SARS-COV2.http://www.sciencedirect.com/science/article/pii/S2214911220300503Novel coronavirus diseaseCOVID-19Acute respiratory distress syndromeTwin pregnancyMechanical ventilationVertical transmission |
| spellingShingle | Harsh Mehta Sasa Ivanovic Amanda Cronin Lindsey VanBrunt Nirav Mistry Richard Miller Paul Yodice Fariborz Rezai Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report Case Reports in Women's Health Novel coronavirus disease COVID-19 Acute respiratory distress syndrome Twin pregnancy Mechanical ventilation Vertical transmission |
| title | Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report |
| title_full | Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report |
| title_fullStr | Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report |
| title_full_unstemmed | Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report |
| title_short | Novel coronavirus-related acute respiratory distress syndrome in a patient with twin pregnancy: A case report |
| title_sort | novel coronavirus related acute respiratory distress syndrome in a patient with twin pregnancy a case report |
| topic | Novel coronavirus disease COVID-19 Acute respiratory distress syndrome Twin pregnancy Mechanical ventilation Vertical transmission |
| url | http://www.sciencedirect.com/science/article/pii/S2214911220300503 |
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