Alternative and Efficient Extraction Methods for Marine-Derived Compounds

Marine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them...

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Main Authors: Clara Grosso, Patrícia Valentão, Federico Ferreres, Paula B. Andrade
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/13/5/3182
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author Clara Grosso
Patrícia Valentão
Federico Ferreres
Paula B. Andrade
author_facet Clara Grosso
Patrícia Valentão
Federico Ferreres
Paula B. Andrade
author_sort Clara Grosso
collection DOAJ
description Marine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them in different bioassays and assess their potential to fight human diseases. Since traditional extraction techniques are both solvent- and time-consuming, this review emphasizes alternative extraction techniques, such as supercritical fluid extraction, pressurized solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, pulsed electric field-assisted extraction, enzyme-assisted extraction, and extraction with switchable solvents and ionic liquids, applied in the search for marine compounds. Only studies published in the 21st century are considered.
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spelling doaj.art-62969cc934514bc5ba8daccc839bd0482022-12-22T02:56:26ZengMDPI AGMarine Drugs1660-33972015-05-011353182323010.3390/md13053182md13053182Alternative and Efficient Extraction Methods for Marine-Derived CompoundsClara Grosso0Patrícia Valentão1Federico Ferreres2Paula B. Andrade3REQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, no. 228, Porto 4050-313, PortugalREQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, no. 228, Porto 4050-313, PortugalResearch Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), P.O. Box 164, 30100 Campus University Espinardo, Murcia 30100, SpainREQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira, no. 228, Porto 4050-313, PortugalMarine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them in different bioassays and assess their potential to fight human diseases. Since traditional extraction techniques are both solvent- and time-consuming, this review emphasizes alternative extraction techniques, such as supercritical fluid extraction, pressurized solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, pulsed electric field-assisted extraction, enzyme-assisted extraction, and extraction with switchable solvents and ionic liquids, applied in the search for marine compounds. Only studies published in the 21st century are considered.http://www.mdpi.com/1660-3397/13/5/3182marine compoundsenzyme-assisted extractionionic liquidsmicrowave-assisted extractionpressurized solvent extractionpulsed electric field-assisted extractionsupercritical fluid extractionultrasound-assisted extractionswitchable solvents
spellingShingle Clara Grosso
Patrícia Valentão
Federico Ferreres
Paula B. Andrade
Alternative and Efficient Extraction Methods for Marine-Derived Compounds
Marine Drugs
marine compounds
enzyme-assisted extraction
ionic liquids
microwave-assisted extraction
pressurized solvent extraction
pulsed electric field-assisted extraction
supercritical fluid extraction
ultrasound-assisted extraction
switchable solvents
title Alternative and Efficient Extraction Methods for Marine-Derived Compounds
title_full Alternative and Efficient Extraction Methods for Marine-Derived Compounds
title_fullStr Alternative and Efficient Extraction Methods for Marine-Derived Compounds
title_full_unstemmed Alternative and Efficient Extraction Methods for Marine-Derived Compounds
title_short Alternative and Efficient Extraction Methods for Marine-Derived Compounds
title_sort alternative and efficient extraction methods for marine derived compounds
topic marine compounds
enzyme-assisted extraction
ionic liquids
microwave-assisted extraction
pressurized solvent extraction
pulsed electric field-assisted extraction
supercritical fluid extraction
ultrasound-assisted extraction
switchable solvents
url http://www.mdpi.com/1660-3397/13/5/3182
work_keys_str_mv AT claragrosso alternativeandefficientextractionmethodsformarinederivedcompounds
AT patriciavalentao alternativeandefficientextractionmethodsformarinederivedcompounds
AT federicoferreres alternativeandefficientextractionmethodsformarinederivedcompounds
AT paulabandrade alternativeandefficientextractionmethodsformarinederivedcompounds