Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease

Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease

Introduction: It has been reported that rapamycin inhibited inflammation in renal interstitial diseases. We therefore hypothesized that rapamycin could attenuate inflammation in polycystic kidney disease (PKD). Methods: Han:SPRD rats were treated with rapamycin by daily gavage from 4 weeks to 12 wee...

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Bibliographic Details
Main Authors: Ming Yang, Jiayi Lv, Chanjuan Gong, Cheng Xue, Lili Fu, Shunjie Chen, Changlin Mei
Format: Article
Language:English
Published: Karger Publishers 2024-01-01
Series:Kidney & Blood Pressure Research
Subjects:
rapamycin
inflammation
cell proliferation
polycystic kidney disease
Online Access:https://beta.karger.com/Article/FullText/535750

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