Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles
Abstract Objectives Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans. Methods Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross‐sectional analysis of 1106 Jackson Heart Study part...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.1031 |
| _version_ | 1797843573386772480 |
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| author | Rachael R. Baiduc Christopher Spankovich Thanh‐Huyen Vu Alberto A. Arteaga Charles Bishop John M. Schweinfurth |
| author_facet | Rachael R. Baiduc Christopher Spankovich Thanh‐Huyen Vu Alberto A. Arteaga Charles Bishop John M. Schweinfurth |
| author_sort | Rachael R. Baiduc |
| collection | DOAJ |
| description | Abstract Objectives Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans. Methods Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross‐sectional analysis of 1106 Jackson Heart Study participants. Hearing loss was defined as puretone average (PTA0.5,1,2,4) > 15 dB HL. Distortion product otoacoustic emissions (DPOAEs) were collected for f2 = 1.0–8.0 kHz. Two amplitude averages were computed: DPOAElow (f2 ≤ 4 kHz) and DPOAEhigh (f2 ≥ 6 kHz). Based on major CVD risk factors (diabetes, current smoking, total cholesterol ≥240 mg/dL or treatment, and systolic blood pressure [BP]/diastolic BP ≥ 140/≥90 mmHg or treatment), four risk groups were created: 0, 1, 2, and ≥3 risk factors. Logistic regression estimated the odds of hearing loss and absent/reduced DPOAElow and DPOAEhigh by CVD risk status adjusting for age, sex, education, BMI, vertigo, and noise exposure. Results With multivariable adjustment, diabetes was associated with hearing loss (OR = 1.48 [95% CI: 1.04–2.10]). However, there was not a statistically significant relationship between CVD risk factors (individually or for overall risk) and DPOAEs. Conclusion Diabetes was associated with hearing loss. Neither individual CVD risk factors nor overall risk showed a relationship to cochlear dysfunction. Level of Evidence 2b. |
| first_indexed | 2024-04-09T17:07:37Z |
| format | Article |
| id | doaj.art-629f8f071bf94ba29dc44e59d163e487 |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-04-09T17:07:37Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-629f8f071bf94ba29dc44e59d163e4872023-04-20T11:45:42ZengWileyLaryngoscope Investigative Otolaryngology2378-80382023-04-018249550410.1002/lio2.1031Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profilesRachael R. Baiduc0Christopher Spankovich1Thanh‐Huyen Vu2Alberto A. Arteaga3Charles Bishop4John M. Schweinfurth5Department of Speech, Language, and Hearing Sciences University of Colorado Boulder Boulder Colorado USADepartment of Otolaryngology and Communicative Sciences University of Mississippi Medical Center Jackson Mississippi USADepartment of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago Illinois USADepartment of Otolaryngology and Communicative Sciences University of Mississippi Medical Center Jackson Mississippi USADepartment of Otolaryngology and Communicative Sciences University of Mississippi Medical Center Jackson Mississippi USADepartment of Otolaryngology and Communicative Sciences University of Mississippi Medical Center Jackson Mississippi USAAbstract Objectives Evaluate the relationship between cardiovascular disease (CVD) risk factors and cochlear function in African Americans. Methods Relationships between hearing loss, cochlear function, and CVD risk factors were assessed in a cross‐sectional analysis of 1106 Jackson Heart Study participants. Hearing loss was defined as puretone average (PTA0.5,1,2,4) > 15 dB HL. Distortion product otoacoustic emissions (DPOAEs) were collected for f2 = 1.0–8.0 kHz. Two amplitude averages were computed: DPOAElow (f2 ≤ 4 kHz) and DPOAEhigh (f2 ≥ 6 kHz). Based on major CVD risk factors (diabetes, current smoking, total cholesterol ≥240 mg/dL or treatment, and systolic blood pressure [BP]/diastolic BP ≥ 140/≥90 mmHg or treatment), four risk groups were created: 0, 1, 2, and ≥3 risk factors. Logistic regression estimated the odds of hearing loss and absent/reduced DPOAElow and DPOAEhigh by CVD risk status adjusting for age, sex, education, BMI, vertigo, and noise exposure. Results With multivariable adjustment, diabetes was associated with hearing loss (OR = 1.48 [95% CI: 1.04–2.10]). However, there was not a statistically significant relationship between CVD risk factors (individually or for overall risk) and DPOAEs. Conclusion Diabetes was associated with hearing loss. Neither individual CVD risk factors nor overall risk showed a relationship to cochlear dysfunction. Level of Evidence 2b.https://doi.org/10.1002/lio2.1031audiologycardiovascular disease risk factorsdistortion product otoacoustic emissionshearing lossJackson Heart Studyotology |
| spellingShingle | Rachael R. Baiduc Christopher Spankovich Thanh‐Huyen Vu Alberto A. Arteaga Charles Bishop John M. Schweinfurth Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles Laryngoscope Investigative Otolaryngology audiology cardiovascular disease risk factors distortion product otoacoustic emissions hearing loss Jackson Heart Study otology |
| title | Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles |
| title_full | Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles |
| title_fullStr | Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles |
| title_full_unstemmed | Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles |
| title_short | Jackson Heart Study: Aggregate cardiovascular disease risk and auditory profiles |
| title_sort | jackson heart study aggregate cardiovascular disease risk and auditory profiles |
| topic | audiology cardiovascular disease risk factors distortion product otoacoustic emissions hearing loss Jackson Heart Study otology |
| url | https://doi.org/10.1002/lio2.1031 |
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