Should the 14‐day rule for embryo research become the 28‐day rule?
The “14‐day rule”—broadly construed—is used in science policy and regulation to limit research on human embryos to a maximum period of 14 days after their creation or to the equivalent stage of development that is normally attributed to a 14‐day‐old embryo (Hyun et al, ; Nuffield Council on Bioethic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2018-09-01
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| Series: | EMBO Molecular Medicine |
| Online Access: | https://doi.org/10.15252/emmm.201809437 |
| _version_ | 1797285191636484096 |
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| author | John B Appleby Annelien L Bredenoord |
| author_facet | John B Appleby Annelien L Bredenoord |
| author_sort | John B Appleby |
| collection | DOAJ |
| description | The “14‐day rule”—broadly construed—is used in science policy and regulation to limit research on human embryos to a maximum period of 14 days after their creation or to the equivalent stage of development that is normally attributed to a 14‐day‐old embryo (Hyun et al, ; Nuffield Council on Bioethics, ). For several decades, the 14‐day rule has been a shining example of how science policy and regulation can be developed with interdisciplinary consensus and applied across a number of countries to help fulfil an ethical and practical purpose: to facilitate efficient and ethical embryo research. However, advances in embryology and biomedical research have led to suggestions that the 14‐day rule is no longer adequate (Deglincerti et al, ; Shahbazi et al, ; Hurlbut et al, ). Therefore, should the 14‐day rule be extended and, if so, where should we draw a new line for permissible embryo research? Here, we provide scientific, regulatory and ethical arguments that the 14‐day rule should be extended to 28 days (or the developmental equivalent stage of a 28‐day‐old embryo). |
| first_indexed | 2024-03-07T17:59:42Z |
| format | Article |
| id | doaj.art-629fc3eb38de46aba845e246397b49ea |
| institution | Directory Open Access Journal |
| issn | 1757-4676 1757-4684 |
| language | English |
| last_indexed | 2024-03-07T17:59:42Z |
| publishDate | 2018-09-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | EMBO Molecular Medicine |
| spelling | doaj.art-629fc3eb38de46aba845e246397b49ea2024-03-02T11:11:30ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842018-09-01109n/an/a10.15252/emmm.201809437Should the 14‐day rule for embryo research become the 28‐day rule?John B Appleby0Annelien L Bredenoord1Lancaster Medical School Lancaster University Lancaster UKDepartment of Medical Humanities Julius Center University Medical Center Utrecht Utrecht The NetherlandsThe “14‐day rule”—broadly construed—is used in science policy and regulation to limit research on human embryos to a maximum period of 14 days after their creation or to the equivalent stage of development that is normally attributed to a 14‐day‐old embryo (Hyun et al, ; Nuffield Council on Bioethics, ). For several decades, the 14‐day rule has been a shining example of how science policy and regulation can be developed with interdisciplinary consensus and applied across a number of countries to help fulfil an ethical and practical purpose: to facilitate efficient and ethical embryo research. However, advances in embryology and biomedical research have led to suggestions that the 14‐day rule is no longer adequate (Deglincerti et al, ; Shahbazi et al, ; Hurlbut et al, ). Therefore, should the 14‐day rule be extended and, if so, where should we draw a new line for permissible embryo research? Here, we provide scientific, regulatory and ethical arguments that the 14‐day rule should be extended to 28 days (or the developmental equivalent stage of a 28‐day‐old embryo).https://doi.org/10.15252/emmm.201809437 |
| spellingShingle | John B Appleby Annelien L Bredenoord Should the 14‐day rule for embryo research become the 28‐day rule? EMBO Molecular Medicine |
| title | Should the 14‐day rule for embryo research become the 28‐day rule? |
| title_full | Should the 14‐day rule for embryo research become the 28‐day rule? |
| title_fullStr | Should the 14‐day rule for embryo research become the 28‐day rule? |
| title_full_unstemmed | Should the 14‐day rule for embryo research become the 28‐day rule? |
| title_short | Should the 14‐day rule for embryo research become the 28‐day rule? |
| title_sort | should the 14 day rule for embryo research become the 28 day rule |
| url | https://doi.org/10.15252/emmm.201809437 |
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