Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung
Abstract Endoplasmic reticulum (ER) stress is a cellular state that results from the overload of unfolded/misfolded protein in the ER that, if not resolved properly, can lead to cell death. Both acute lung infections and chronic lung diseases have been found related to ER stress. Yet no study has be...
Main Authors: | Zijing Wang, Peng Ma, Yisa Wang, Biyu Hou, Can Zhou, He Tian, Bowen Li, Guanghou Shui, Xiuying Yang, Guifen Qiang, Chengqian Yin, Guanhua Du |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-92779-8 |
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