Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life
The aim of the study was to compare the effect of the administration of antibiotics or probiotics on chickens in their first week of life, on selected parameters of humoral and cellular immunity, and on the bursa of Fabricius and spleen indices. The experiment was carried out on 90 one-day-old male...
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MDPI AG
2022-04-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/9/1133 |
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| author | Jan Jankowski Bartłomiej Tykałowski Anna Stępniowska Paweł Konieczka Andrzej Koncicki Paulius Matusevičius Katarzyna Ognik |
| author_facet | Jan Jankowski Bartłomiej Tykałowski Anna Stępniowska Paweł Konieczka Andrzej Koncicki Paulius Matusevičius Katarzyna Ognik |
| author_sort | Jan Jankowski |
| collection | DOAJ |
| description | The aim of the study was to compare the effect of the administration of antibiotics or probiotics on chickens in their first week of life, on selected parameters of humoral and cellular immunity, and on the bursa of Fabricius and spleen indices. The experiment was carried out on 90 one-day-old male broilers. The control group received no additive in the drinking water; the group GP received a probiotic providing <i>Enterococcus faecium</i> and <i>Bacillus amyloliquefaciens</i>; and the group GA received 10% enrofloxacin in the drinking water on the first five days of life. Administration of the antibiotic enrofloxacin or a probiotic containing <i>E. faecium</i> and <i>B. amyloliquefaciens</i> strains to chickens in their first week of life exerts pronounced immunomodulatory effects on humoral and cellular defense mechanisms in these birds. The changes in the subpopulations of B and T cells immediately following early administration of enrofloxacin or the probiotic were not observed at the age of 35 days. Early administration of enrofloxacin can pose a risk of suppression of humoral immunity, as indicated by the significant decrease in the total IgY concentration in the plasma of the chickens. |
| first_indexed | 2024-03-10T04:23:52Z |
| format | Article |
| id | doaj.art-62a0b177d8a04c4cb1ecf6eb4b03a315 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T04:23:52Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-62a0b177d8a04c4cb1ecf6eb4b03a3152023-11-23T07:42:49ZengMDPI AGAnimals2076-26152022-04-01129113310.3390/ani12091133Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early LifeJan Jankowski0Bartłomiej Tykałowski1Anna Stępniowska2Paweł Konieczka3Andrzej Koncicki4Paulius Matusevičius5Katarzyna Ognik6Department of Poultry Science and Apiculture, Faculty of Animal Bioengineering, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, PolandDepartment of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, PolandDepartment of Biochemistry and Toxicology, Faculty of Animal Science and Bioeconomy, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, PolandDepartment of Poultry Science and Apiculture, Faculty of Animal Bioengineering, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, PolandDepartment of Poultry Diseases, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, PolandDepartment of Animal Nutrition, Lithuanian University of Health Sciences, Kaunas, Tilzes 18, LT-47181 Kaunas, LithuaniaDepartment of Biochemistry and Toxicology, Faculty of Animal Science and Bioeconomy, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, PolandThe aim of the study was to compare the effect of the administration of antibiotics or probiotics on chickens in their first week of life, on selected parameters of humoral and cellular immunity, and on the bursa of Fabricius and spleen indices. The experiment was carried out on 90 one-day-old male broilers. The control group received no additive in the drinking water; the group GP received a probiotic providing <i>Enterococcus faecium</i> and <i>Bacillus amyloliquefaciens</i>; and the group GA received 10% enrofloxacin in the drinking water on the first five days of life. Administration of the antibiotic enrofloxacin or a probiotic containing <i>E. faecium</i> and <i>B. amyloliquefaciens</i> strains to chickens in their first week of life exerts pronounced immunomodulatory effects on humoral and cellular defense mechanisms in these birds. The changes in the subpopulations of B and T cells immediately following early administration of enrofloxacin or the probiotic were not observed at the age of 35 days. Early administration of enrofloxacin can pose a risk of suppression of humoral immunity, as indicated by the significant decrease in the total IgY concentration in the plasma of the chickens.https://www.mdpi.com/2076-2615/12/9/1133chickenantibioticprobioticimmune response |
| spellingShingle | Jan Jankowski Bartłomiej Tykałowski Anna Stępniowska Paweł Konieczka Andrzej Koncicki Paulius Matusevičius Katarzyna Ognik Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life Animals chicken antibiotic probiotic immune response |
| title | Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life |
| title_full | Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life |
| title_fullStr | Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life |
| title_full_unstemmed | Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life |
| title_short | Immune Parameters in Chickens Treated with Antibiotics and Probiotics during Early Life |
| title_sort | immune parameters in chickens treated with antibiotics and probiotics during early life |
| topic | chicken antibiotic probiotic immune response |
| url | https://www.mdpi.com/2076-2615/12/9/1133 |
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