Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021
ObjectiveEpidemiological characteristics of COVID-19 outbreak in Yangzhou city caused by the highly contagious Delta variant strain of SARS-CoV-2 virus were investigated in this retrospective descriptive study to provide prevention and control guidelines for outbreaks in the future.MethodsAll the ep...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.865963/full |
| _version_ | 1811305332497973248 |
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| author | Yu-Dong Zhang Ding Chen Lei Hu Liang Shen Ren-Yuan Wu Fu-Ming Cao Jian-Qiang Xu Liang Wang |
| author_facet | Yu-Dong Zhang Ding Chen Lei Hu Liang Shen Ren-Yuan Wu Fu-Ming Cao Jian-Qiang Xu Liang Wang |
| author_sort | Yu-Dong Zhang |
| collection | DOAJ |
| description | ObjectiveEpidemiological characteristics of COVID-19 outbreak in Yangzhou city caused by the highly contagious Delta variant strain of SARS-CoV-2 virus were investigated in this retrospective descriptive study to provide prevention and control guidelines for outbreaks in the future.MethodsAll the epidemiological data used in this study were collected manually from the official website of the Yangzhou Municipal Health Committee from 28 July to 26 August 2021, and then were analyzed systematically and statistically in this study.ResultsA total of 570 COVID-19 cases were reported during the short-term outbreak in Yangzhou City. The ages of infected individuals ranged from 1 to 90 years with the average age at 49.47 ± 22.69 years. As for gender distributions, the ratio of male- to-female patients was 1:1.36 (242:328). Geographic analysis showed that 377 patients (66.1%) were in Hanjiang District while 188 patients (33.0%) were in Guangling District. Clinical diagnosis showed that 175 people (30.7%) had mild symptoms, 385 people were in moderate conditions (67.5%), and 10 people were in severe situations (1.8%). Significant age differences were found among the three groups (P < 0.001). However, no significant difference was identified in terms of gender ratio (P > 0.05). Based on the transmission chain formed by 6 generations of infected persons with a clear transmission relationship, the age showed a gradually decreasing trend, while the median time of diagnosis in 2 adjacent generations was 3 days. In addition, the estimated basic reproduction number R0 of the Delta variant was 3.3651 by the classical Susceptible, Infectious, and/or Recovered (SIR) model.ConclusionThe Delta variant of SARS-CoV-2 was highly infectious and has obvious clustering characteristics during the Yangzhou outbreak in China. |
| first_indexed | 2024-04-13T08:23:33Z |
| format | Article |
| id | doaj.art-62a233d9414347af934c06aa23bfd540 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-13T08:23:33Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-62a233d9414347af934c06aa23bfd5402022-12-22T02:54:33ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-05-011310.3389/fmicb.2022.865963865963Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021Yu-Dong Zhang0Ding Chen1Lei Hu2Liang Shen3Ren-Yuan Wu4Fu-Ming Cao5Jian-Qiang Xu6Liang Wang7The First Clinical Medical College of Xuzhou Medical University, Xuzhou, ChinaSchool of Medical Informatics and Engineering, Xuzhou, ChinaSchool of Mathematics, China University of Mining and Technology, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaSchool of Medical Imaging, Xuzhou Medical University, Xuzhou, ChinaThe Second Clinical Medical College of Xuzhou Medical University, Xuzhou, ChinaSchool of Management, Xuzhou Medical University, Xuzhou, ChinaSchool of Medical Informatics and Engineering, Xuzhou, ChinaObjectiveEpidemiological characteristics of COVID-19 outbreak in Yangzhou city caused by the highly contagious Delta variant strain of SARS-CoV-2 virus were investigated in this retrospective descriptive study to provide prevention and control guidelines for outbreaks in the future.MethodsAll the epidemiological data used in this study were collected manually from the official website of the Yangzhou Municipal Health Committee from 28 July to 26 August 2021, and then were analyzed systematically and statistically in this study.ResultsA total of 570 COVID-19 cases were reported during the short-term outbreak in Yangzhou City. The ages of infected individuals ranged from 1 to 90 years with the average age at 49.47 ± 22.69 years. As for gender distributions, the ratio of male- to-female patients was 1:1.36 (242:328). Geographic analysis showed that 377 patients (66.1%) were in Hanjiang District while 188 patients (33.0%) were in Guangling District. Clinical diagnosis showed that 175 people (30.7%) had mild symptoms, 385 people were in moderate conditions (67.5%), and 10 people were in severe situations (1.8%). Significant age differences were found among the three groups (P < 0.001). However, no significant difference was identified in terms of gender ratio (P > 0.05). Based on the transmission chain formed by 6 generations of infected persons with a clear transmission relationship, the age showed a gradually decreasing trend, while the median time of diagnosis in 2 adjacent generations was 3 days. In addition, the estimated basic reproduction number R0 of the Delta variant was 3.3651 by the classical Susceptible, Infectious, and/or Recovered (SIR) model.ConclusionThe Delta variant of SARS-CoV-2 was highly infectious and has obvious clustering characteristics during the Yangzhou outbreak in China.https://www.frontiersin.org/articles/10.3389/fmicb.2022.865963/fullCOVID-19SARS-CoV-2epidemiologyoutbreakbasic reproduction number |
| spellingShingle | Yu-Dong Zhang Ding Chen Lei Hu Liang Shen Ren-Yuan Wu Fu-Ming Cao Jian-Qiang Xu Liang Wang Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 Frontiers in Microbiology COVID-19 SARS-CoV-2 epidemiology outbreak basic reproduction number |
| title | Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 |
| title_full | Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 |
| title_fullStr | Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 |
| title_full_unstemmed | Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 |
| title_short | Epidemiological Characteristics of COVID-19 Outbreak in Yangzhou, China, 2021 |
| title_sort | epidemiological characteristics of covid 19 outbreak in yangzhou china 2021 |
| topic | COVID-19 SARS-CoV-2 epidemiology outbreak basic reproduction number |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.865963/full |
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