THE EFFECT OF POLYMORPHISM IN GLUTATHIONE S-TRANSFERASES ON THE DEVELOPING SECOND MALIGNANT NEOPLASMS AFTER LEUKEMIA TREATMENT IN CHILDHOOD

THE EFFECT OF POLYMORPHISM IN GLUTATHIONE S-TRANSFERASES ON THE DEVELOPING SECOND MALIGNANT NEOPLASMS AFTER LEUKEMIA TREATMENT IN CHILDHOOD

<p>Background. Survivors of childhood leukemia have an increased risk of developing second malignant neoplasms and specific treatment factors such as alkylating agents, topoisomerase inhibitors and radiation have been associated with their occurrence. Genetic polymorphism in drug-metabolizing...

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Bibliographic Details
Main Authors: Janez Jazbec, Vita Dolžan, Maruša Debeljak, Richard Aplenc, Berta Jereb
Format: Article
Language:English
Published: Slovenian Medical Association 2004-12-01
Series:Zdravniški Vestnik
Subjects:
gluthatione S-transferase
childhood leukemia
secondary neoplasm
Online Access:http://vestnik.szd.si/index.php/ZdravVest/article/view/2416

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