Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis

Portal hypertension is a major pathophysiological condition in patients with cirrhosis. This accounts for the occurrence and severity of the various manifestations. The degree is determined by the portal pressure or hepatic venous pressure gradients, both of which are obtained by invasive interventi...

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Main Authors: Hitoshi Maruyama, Maki Tobari, Hiroaki Nagamatsu, Suichiro Shiina, Tadashi Yamaguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1057045/full
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author Hitoshi Maruyama
Maki Tobari
Hiroaki Nagamatsu
Suichiro Shiina
Tadashi Yamaguchi
author_facet Hitoshi Maruyama
Maki Tobari
Hiroaki Nagamatsu
Suichiro Shiina
Tadashi Yamaguchi
author_sort Hitoshi Maruyama
collection DOAJ
description Portal hypertension is a major pathophysiological condition in patients with cirrhosis. This accounts for the occurrence and severity of the various manifestations. The degree is determined by the portal pressure or hepatic venous pressure gradients, both of which are obtained by invasive interventional radiological procedures. Ultrasound (US) is a simple and minimally invasive imaging modality for the diagnosis of liver diseases. Owing to the availability of microbubble-based contrast agents and the development of imaging modes corresponding to contrast effects, contrast-enhanced US (CEUS) has become popular worldwide for the detailed evaluation of hepatic hemodynamics, diffuse liver disease, and focal hepatic lesions. Recent advancements in digital technology have enabled contrast-based demonstrations with improved resolution, leading to a wider range of applications. This review article describes the current role, benefits, and limitations of CEUS in the management of portal hypertension.
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spelling doaj.art-62a3e36938d54ed3ab4432a11aeb598a2022-12-22T04:23:09ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-12-01910.3389/fmed.2022.10570451057045Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosisHitoshi Maruyama0Maki Tobari1Hiroaki Nagamatsu2Suichiro Shiina3Tadashi Yamaguchi4Department of Gastroenterology, Juntendo University, Tokyo, JapanDepartment of Gastroenterology, Juntendo University, Tokyo, JapanDepartment of Gastroenterology, Juntendo University, Tokyo, JapanDepartment of Gastroenterology, Juntendo University, Tokyo, JapanCenter for Frontier Medical Engineering, Chiba University, Chiba, JapanPortal hypertension is a major pathophysiological condition in patients with cirrhosis. This accounts for the occurrence and severity of the various manifestations. The degree is determined by the portal pressure or hepatic venous pressure gradients, both of which are obtained by invasive interventional radiological procedures. Ultrasound (US) is a simple and minimally invasive imaging modality for the diagnosis of liver diseases. Owing to the availability of microbubble-based contrast agents and the development of imaging modes corresponding to contrast effects, contrast-enhanced US (CEUS) has become popular worldwide for the detailed evaluation of hepatic hemodynamics, diffuse liver disease, and focal hepatic lesions. Recent advancements in digital technology have enabled contrast-based demonstrations with improved resolution, leading to a wider range of applications. This review article describes the current role, benefits, and limitations of CEUS in the management of portal hypertension.https://www.frontiersin.org/articles/10.3389/fmed.2022.1057045/fullultrasoundcontrast agentliverportal hypertensioncirrhosis
spellingShingle Hitoshi Maruyama
Maki Tobari
Hiroaki Nagamatsu
Suichiro Shiina
Tadashi Yamaguchi
Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
Frontiers in Medicine
ultrasound
contrast agent
liver
portal hypertension
cirrhosis
title Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
title_full Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
title_fullStr Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
title_full_unstemmed Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
title_short Contrast-enhanced ultrasonography for the management of portal hypertension in cirrhosis
title_sort contrast enhanced ultrasonography for the management of portal hypertension in cirrhosis
topic ultrasound
contrast agent
liver
portal hypertension
cirrhosis
url https://www.frontiersin.org/articles/10.3389/fmed.2022.1057045/full
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AT suichiroshiina contrastenhancedultrasonographyforthemanagementofportalhypertensionincirrhosis
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