Antibiotic Tolerance and Treatment Outcomes in Cystic Fibrosis Methicillin-Resistant Staphylococcus aureus Infections

Antibiotic Tolerance and Treatment Outcomes in Cystic Fibrosis Methicillin-Resistant Staphylococcus aureus Infections

ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in U.S. cystic fibrosis (CF) patients and is associated with worse clinical outcomes in CF. These infections often become chronic despite repeated antibiotic therapy. Here, we assessed whether bacterial phenotypes, inclu...

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Bibliographic Details
Main Authors: Kuan-Yi Lu, Nikki J. Wagner, Amanda Z. Velez, Agathe Ceppe, Brian P. Conlon, Marianne S. Muhlebach
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
antibiotic tolerance
MRSA
cystic fibrosis
persistence
treatment outcome
Staphylococcus aureus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04061-22

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