Brain Oxygen Perfusion and Oxidative Stress Biomarkers in Fetuses with Congenital Heart Disease—A Retrospective, Case-Control Pilot Study

Brain Oxygen Perfusion and Oxidative Stress Biomarkers in Fetuses with Congenital Heart Disease—A Retrospective, Case-Control Pilot Study

Fetuses with congenital heart disease (CHD) have circulatory changes that may lead to predictable blood flow disturbances that may affect normal brain development. Hypoxemia and hypoperfusion may alter the redox balance leading to oxidative stress (OS), that can be assessed measuring stable end-prod...

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Bibliographic Details
Main Authors: Maria C. Escobar-Diaz, Miriam Pérez-Cruz, Miguel Arráez, Mari-Merce Cascant-Vilaplana, Abel Albiach-Delgado, Julia Kuligowski, Máximo Vento, Narcis Masoller, Maria Dolores Gómez-Roig, Olga Gómez, Joan Sanchez-de-Toledo, Marta Camprubí-Camprubí
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
congenital heart disease
hypoxia
brain perfusion
reactive oxygen species
ortho-Tyrosine
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/11/2/299

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